SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		3 / 3 ARG A 218
VAL A 190
GLY A 181
 None
 0.59A 2avvE-1tqjA:
undetectable		 2avvE-1tqjA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		5 / 12 ALA A 115
ALA A 117
HIS A 100
LEU A 101
VAL A 131
 None
 0.78A 2yqzB-1tqjA:
undetectable		 2yqzB-1tqjA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		5 / 12 THR A 123
LEU A 119
ASN A  96
VAL A 134
LEU A 105
 None
 1.37A 3a51B-1tqjA:
undetectable		 3a51B-1tqjA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		4 / 4 PHE A 127
TYR A 130
VAL A 178
LEU A 139
 None
 1.33A 3keeD-1tqjA:
0.0		 3keeD-1tqjA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		3 / 3 HIS A  68
HIS A  92
MET A  70
 None
 0.73A 3mihA-1tqjA:
undetectable		 3mihA-1tqjA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		3 / 3 VAL A 178
SER A 142
LEU A 182
 None
 0.67A 3n8xA-1tqjA:
undetectable		 3n8xA-1tqjA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		5 / 9 GLY A  85
ALA A  86
ASP A  87
ILE A  88
ILE A  57
 None
 0.85A 3ogpA-1tqjA:
undetectable		 3ogpA-1tqjA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		5 / 12 ILE A  49
ALA A  84
HIS A  68
VAL A  36
ILE A  11
 None
 1.11A 4rvdA-1tqjA:
undetectable		 4rvdA-1tqjA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA302_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		4 / 5 PRO A 145
MET A  70
HIS A  68
LEU A 139
 None
 1.34A 4ww7A-1tqjA:
0.0		 4ww7A-1tqjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		5 / 8 ALA A  31
PRO A   9
VAL A   7
GLY A  30
ALA A  29
 None
 1.15A 4zjzB-1tqjA:
undetectable		 4zjzB-1tqjA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		4 / 6 LYS A  76
TYR A  77
PRO A  51
LEU A  69
 None
 1.30A 5bmvB-1tqjA:
undetectable		 5bmvB-1tqjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		4 / 7 ALA A   8
PHE A  81
ILE A  89
ILE A  49
 None
 0.88A 6b5vA-1tqjA:
undetectable
6b5vB-1tqjA:
undetectable		 6b5vA-1tqjA:
16.67
6b5vB-1tqjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE
(Synechocystis
sp.) 		3 / 3 ASP A 179
SER A 202
SER A  13
 None
 0.78A 6mxtA-1tqjA:
undetectable		 6mxtA-1tqjA:
18.24