SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.74A 1p7lD-1tsjA:
undetectable
1p7lD-1tsjA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.75A 1p7lC-1tsjA:
undetectable
1p7lC-1tsjA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.73A 1rg9B-1tsjA:
undetectable
1rg9B-1tsjA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.74A 1rg9A-1tsjA:
undetectable
1rg9A-1tsjA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.73A 1rg9D-1tsjA:
undetectable
1rg9D-1tsjA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.74A 1rg9C-1tsjA:
undetectable
1rg9C-1tsjA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 PHE A  12
ALA A  16
THR A  24
LEU A  56
None
0.84A 2wx2B-1tsjA:
undetectable
2wx2B-1tsjA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.79A 4kttB-1tsjA:
undetectable
4kttB-1tsjA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.75A 4kttD-1tsjA:
undetectable
4kttD-1tsjA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.81A 4ndnB-1tsjA:
undetectable
4ndnB-1tsjA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.77A 4ndnD-1tsjA:
undetectable
4ndnD-1tsjA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 8 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.77A 5t8sA-1tsjA:
undetectable
5t8sA-1tsjA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1tsj CONSERVED
HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
4 / 7 ALA A 130
ASP A   2
ILE A   3
ILE A  53
None
0.84A 6fbnA-1tsjA:
undetectable
6fbnA-1tsjA:
16.11