SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tt7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 LEU A 191
ALA A 196
VAL A 178
VAL A 156
 None
 0.86A 1epbA-1tt7A:
undetectable		 1epbA-1tt7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 LEU A 122
GLY A  71
VAL A 108
LEU A 113
LEU A  94
 None
 1.34A 1mx1E-1tt7A:
undetectable		 1mx1E-1tt7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 10 LEU A 171
ALA A 135
VAL A 154
LEU A 142
ASP A 291
 None
 1.26A 1rlbE-1tt7A:
undetectable		 1rlbE-1tt7A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 THR A 134
THR A 130
SER A  91
VAL A  96
 None
 1.10A 1tv8A-1tt7A:
undetectable		 1tv8A-1tt7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 THR A 134
THR A 130
SER A  91
VAL A  96
 None
 1.10A 1tv8B-1tt7A:
undetectable		 1tv8B-1tt7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 LEU A 233
GLY A 152
VAL A 243
ILE A 237
 None
 0.74A 2aojB-1tt7A:
undetectable		 2aojB-1tt7A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 8 THR A 134
THR A 130
SER A  91
VAL A  96
 None
 1.08A 2fb2A-1tt7A:
undetectable		 2fb2A-1tt7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 THR A 134
THR A 130
SER A  91
VAL A  96
 None
 1.08A 2fb2B-1tt7A:
undetectable		 2fb2B-1tt7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A 195
ALA A 196
GLY A 164
GLY A 165
ILE A 300
 None
 0.86A 2fxeA-1tt7A:
undetectable		 2fxeA-1tt7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 PHE A   5
ILE A  43
LEU A 314
ASP A  47
GLY A  66
 None
 1.30A 2ycjA-1tt7A:
undetectable		 2ycjA-1tt7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		3 / 3 GLY A 101
GLY A  95
GLY A  66
 None
 0.38A 3bogC-1tt7A:
undetectable		 3bogC-1tt7A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		3 / 3 GLY A 101
GLY A  95
GLY A  66
 None
 0.32A 3bogD-1tt7A:
undetectable		 3bogD-1tt7A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 4 GLU A  83
GLY A  84
THR A  72
GLU A  86
 None
 1.13A 3e9xA-1tt7A:
undetectable		 3e9xA-1tt7A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 4 GLY A  42
VAL A 326
GLY A 161
THR A 160
 None
 0.94A 3ib2A-1tt7A:
undetectable		 3ib2A-1tt7A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 10 TYR A 176
SER A 138
SER A 242
LEU A 147
GLY A 270
 None
 1.38A 3lsfB-1tt7A:
0.3
3lsfE-1tt7A:
0.0		 3lsfB-1tt7A:
23.32
3lsfE-1tt7A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 ASN A 172
LEU A 155
GLY A 152
ILE A 200
VAL A 178
 None
 1.09A 3nk7A-1tt7A:
2.5		 3nk7A-1tt7A:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		3 / 3 ASN A  44
ALA A 131
ARG A 325
 None
 0.86A 3tj7C-1tt7A:
undetectable
3tj7D-1tt7A:
undetectable		 3tj7C-1tt7A:
23.74
3tj7D-1tt7A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A 161
GLY A 164
GLY A 165
LEU A 194
GLY A 158
 None
 0.84A 4o33A-1tt7A:
4.5		 4o33A-1tt7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A 162
GLY A 164
GLY A 165
LEU A 194
GLY A 158
 None
 0.86A 4o33A-1tt7A:
4.5		 4o33A-1tt7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A 162
GLY A 164
GLY A 165
LEU A 194
GLY A 158
 None
 0.85A 4o3fA-1tt7A:
3.3		 4o3fA-1tt7A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 9 ALA A 167
ASN A 320
GLY A 161
SER A 246
VAL A 225
 None
 1.24A 4r20B-1tt7A:
undetectable		 4r20B-1tt7A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1tt7 YHFP
(Bacillus
subtilis) 		3 / 3 SER A  91
ASP A 223
ASP A 272
 None
 0.79A 4uckA-1tt7A:
undetectable		 4uckA-1tt7A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A  95
GLY A 100
GLY A 101
LEU A 102
ASP A  47
 None
 0.92A 5c0oF-1tt7A:
6.8		 5c0oF-1tt7A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A 129
ILE A  43
GLY A  66
ILE A  67
GLY A  71
 None
 0.96A 5d4uC-1tt7A:
6.4		 5d4uC-1tt7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 TYR A  40
ILE A  43
GLY A  66
ILE A  67
GLY A  71
 None
 0.92A 5d4uC-1tt7A:
6.4		 5d4uC-1tt7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 TYR A  40
ILE A  43
GLY A  66
ILE A  67
GLY A  71
 None
 1.01A 5d4uD-1tt7A:
6.4		 5d4uD-1tt7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 VAL A 205
LEU A 147
GLY A 220
ALA A 221
LEU A 233
 None
 1.31A 5iktB-1tt7A:
undetectable		 5iktB-1tt7A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 1tt7 YHFP
(Bacillus
subtilis) 		3 / 3 LYS A 151
GLN A 144
ASN A 145
 None
 0.75A 5l2tA-1tt7A:
undetectable		 5l2tA-1tt7A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 ALA A  69
GLY A 101
GLN A   9
GLU A  11
LEU A  63
 None
 1.20A 5nwuA-1tt7A:
undetectable		 5nwuA-1tt7A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 VAL A  96
TYR A 275
GLU A  93
SER A  97
 None
 1.20A 5umwA-1tt7A:
undetectable
5umwF-1tt7A:
undetectable		 5umwA-1tt7A:
14.55
5umwF-1tt7A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 10 PRO A 115
ALA A  70
GLY A 129
THR A 130
ALA A  89
 None
 1.29A 5vyhA-1tt7A:
undetectable		 5vyhA-1tt7A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 4 VAL A  21
LEU A   8
LEU A 102
ASP A  47
 None
 1.47A 5xv7A-1tt7A:
0.0		 5xv7A-1tt7A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 5 VAL A 284
TRP A 285
PRO A 117
THR A 134
 None
 1.41A 6cduA-1tt7A:
0.0
6cduB-1tt7A:
0.0		 6cduA-1tt7A:
23.81
6cduB-1tt7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 6 VAL A 168
PRO A 294
ALA A 159
THR A 160
 None
 0.84A 6cduB-1tt7A:
0.0
6cduC-1tt7A:
0.0		 6cduB-1tt7A:
23.81
6cduC-1tt7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 8 VAL A 168
PRO A 294
ALA A 159
THR A 160
 None
 0.92A 6cduD-1tt7A:
undetectable
6cduE-1tt7A:
undetectable		 6cduD-1tt7A:
23.81
6cduE-1tt7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1tt7 YHFP
(Bacillus
subtilis) 		4 / 7 ALA A 159
THR A 160
VAL A 168
PRO A 294
 None
 0.93A 6cduF-1tt7A:
undetectable
6cduJ-1tt7A:
undetectable		 6cduF-1tt7A:
23.81
6cduJ-1tt7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 LEU A 233
LEU A 230
ALA A 159
LEU A 155
LEU A 171
 None
 0.96A 6ew0B-1tt7A:
2.5		 6ew0B-1tt7A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 LEU A 233
LEU A 230
ALA A 159
LEU A 155
LEU A 171
 None
 0.96A 6ew0D-1tt7A:
2.5		 6ew0D-1tt7A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 LEU A 233
LEU A 230
ALA A 159
LEU A 155
LEU A 171
 None
 0.96A 6ew0H-1tt7A:
2.7		 6ew0H-1tt7A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 LEU A 233
LEU A 230
ALA A 159
LEU A 155
LEU A 171
 None
 0.95A 6ew0I-1tt7A:
2.5		 6ew0I-1tt7A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 1tt7 YHFP
(Bacillus
subtilis) 		5 / 12 GLY A  48
GLY A  51
ALA A  53
ILE A  43
LEU A  65
 None
 1.06A 6iftA-1tt7A:
4.6		 6iftA-1tt7A:
22.71