SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ttx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		5 / 11 PHE A  30
VAL A 107
PHE A  31
ILE A  51
PHE A  67
 None
 1.05A 1z11B-1ttxA:
undetectable		 1z11B-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 8 LEU A  64
LEU A  36
ILE A  98
PHE A 103
 None
 0.84A 3ln1A-1ttxA:
undetectable		 3ln1A-1ttxA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 7 LEU A  64
LEU A  36
ILE A  98
PHE A 103
 None
 0.84A 3ln1B-1ttxA:
undetectable		 3ln1B-1ttxA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		5 / 10 PHE A  30
VAL A 107
PHE A  31
ILE A  51
PHE A  67
 None
 1.13A 3t3qA-1ttxA:
undetectable		 3t3qA-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		5 / 10 PHE A  30
VAL A 107
PHE A  31
ILE A  51
PHE A  67
 None
 1.10A 3t3qB-1ttxA:
undetectable		 3t3qB-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		5 / 10 PHE A  30
VAL A 107
PHE A  31
ILE A  51
PHE A  67
 None
 1.09A 3t3qC-1ttxA:
undetectable		 3t3qC-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		5 / 10 PHE A  30
VAL A 107
PHE A  31
ILE A  51
PHE A  67
 None
 1.07A 3t3qD-1ttxA:
undetectable		 3t3qD-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 5 LEU A  59
ALA A 100
PHE A  48
ASN A  92
 None
 1.28A 3uq6A-1ttxA:
undetectable		 3uq6A-1ttxA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 7 ILE A  51
PHE A  30
PHE A  31
LEU A  36
 None
 0.68A 3v7pA-1ttxA:
undetectable		 3v7pA-1ttxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 4 LEU A  59
ALA A 100
PHE A  48
ASN A  92
 None
 1.27A 3vaqA-1ttxA:
undetectable		 3vaqA-1ttxA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 4 LEU A  59
ALA A 100
PHE A  48
ASN A  92
 None
 1.28A 3vasA-1ttxA:
undetectable		 3vasA-1ttxA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 7 PHE A  30
PHE A  71
ILE A  51
PHE A  67
 None
 0.82A 4ejjA-1ttxA:
undetectable		 4ejjA-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 7 PHE A  30
VAL A 107
PHE A  71
PHE A  67
 None
 0.97A 4ejjB-1ttxA:
undetectable		 4ejjB-1ttxA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 1ttx ONCOMODULIN
(Homo
sapiens) 		3 / 3 SER A 109
MET A 106
ASP A  11
 None
 0.72A 4mm4B-1ttxA:
undetectable		 4mm4B-1ttxA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 1ttx ONCOMODULIN
(Homo
sapiens) 		5 / 12 VAL A  44
PHE A  67
LEU A  68
VAL A 107
SER A   8
 None
 1.20A 4po0A-1ttxA:
undetectable		 4po0A-1ttxA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 1ttx ONCOMODULIN
(Homo
sapiens) 		4 / 7 LEU A   7
ASP A  10
ALA A  13
LEU A  16
 None
 1.10A 5nwvA-1ttxA:
0.0		 5nwvA-1ttxA:
18.48