SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		3 / 3 GLU A 123
THR A 128
LEU A 169
 None
 0.61A 1v8bC-1tuaA:
undetectable		 1v8bC-1tuaA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		5 / 12 VAL A  96
GLN A  95
ILE A 111
VAL A 137
VAL A  90
 None
 1.16A 3iw1A-1tuaA:
undetectable		 3iw1A-1tuaA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		4 / 7 SER A  70
VAL A  66
VAL A  17
LEU A  14
 None
 0.88A 3o14A-1tuaA:
undetectable		 3o14A-1tuaA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		5 / 9 LEU A 156
ILE A 111
MET A 125
TYR A 129
ILE A 112
 None
 1.26A 3zosB-1tuaA:
undetectable		 3zosB-1tuaA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		4 / 5 LEU A  82
ARG A  31
ILE A  69
ASN A 131
 None
 1.20A 4i00A-1tuaA:
undetectable		 4i00A-1tuaA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		4 / 7 VAL A  24
ILE A  28
LEU A  88
LEU A  81
 None
 0.88A 4l1wA-1tuaA:
undetectable		 4l1wA-1tuaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		4 / 7 VAL A  24
ILE A  28
LEU A  88
LEU A  81
 None
 1.01A 4xo7A-1tuaA:
undetectable		 4xo7A-1tuaA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		4 / 4 VAL A  57
ALA A  62
ILE A  54
THR A  34
 None
 1.01A 5e4dB-1tuaA:
1.7		 5e4dB-1tuaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1tua HYPOTHETICAL PROTEIN
APE0754
(Aeropyrum
pernix) 		4 / 5 LEU A  88
VAL A  90
GLU A 136
LEU A  71
 None
 0.81A 5xooB-1tuaA:
undetectable		 5xooB-1tuaA:
18.85