SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR B 111
THR B 108
PRO B 110
 None
 0.87A 1a7yB-1tueB:
undetectable		 1a7yB-1tueB:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 ALA B 154
VAL B 141
TRP B 138
 None
 0.95A 1av2A-1tueB:
undetectable
1av2B-1tueB:
undetectable		 1av2A-1tueB:
5.70
1av2B-1tueB:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 PHE B 114
TRP B  96
GLU B  94
 None
 1.04A 1mogA-1tueB:
undetectable		 1mogA-1tueB:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 11 SER A 511
PHE A 539
TYR A 538
LEU A 564
THR A 523
 None
 1.23A 1mxfB-1tueA:
undetectable		 1mxfB-1tueA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 11 SER A 511
PHE A 539
TYR A 538
LEU A 564
THR A 523
 None
 1.24A 1mxfC-1tueA:
undetectable		 1mxfC-1tueA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 12 THR A 591
PHE A 482
PHE A 463
LEU A 627
PHE A 619
 None
 1.06A 1q23A-1tueA:
undetectable
1q23B-1tueA:
undetectable		 1q23A-1tueA:
22.54
1q23B-1tueA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 12 THR A 591
PHE A 482
PHE A 463
LEU A 627
PHE A 619
 None
 1.06A 1q23D-1tueA:
undetectable
1q23E-1tueA:
undetectable		 1q23D-1tueA:
22.54
1q23E-1tueA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR B 111
THR B 108
PRO B 110
 None
 0.85A 1unjF-1tueB:
undetectable		 1unjF-1tueB:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 ALA B 154
VAL B 141
TRP B 138
 None
 0.94A 1w5uA-1tueB:
undetectable
1w5uB-1tueB:
undetectable		 1w5uA-1tueB:
5.70
1w5uB-1tueB:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 12 ILE A 433
PHE A 482
LEU A 570
ALA A 466
PHE A 463
 None
 1.46A 3apwB-1tueA:
undetectable		 3apwB-1tueA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 TRP B 138
ALA B 154
VAL B 141
 None
 0.99A 3l8lC-1tueB:
undetectable
3l8lD-1tueB:
undetectable		 3l8lC-1tueB:
5.70
3l8lD-1tueB:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY B 161
TRP B 189
VAL B 123
 None
 0.64A 3n62B-1tueB:
undetectable		 3n62B-1tueB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY B 161
TRP B 189
VAL B 123
 None
 0.63A 3n65B-1tueB:
undetectable		 3n65B-1tueB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY B 161
TRP B 189
VAL B 123
 None
 0.64A 3n66B-1tueB:
3.2		 3n66B-1tueB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		4 / 5 GLY B 161
ILE B 174
TRP B 189
VAL B 191
 None
 1.07A 4d33A-1tueB:
1.8		 4d33A-1tueB:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		4 / 8 THR B 149
TRP B 150
ASP B 151
TYR B 142
 None
 1.08A 4drjB-1tueB:
4.3		 4drjB-1tueB:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		4 / 5 ARG A 434
LEU A 627
SER A 625
MET A 429
 None
 1.14A 4e1gA-1tueA:
undetectable		 4e1gA-1tueA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 THR B 145
ASP B 146
ALA B 147
 None
 0.00A 5g5gB-1tueB:
undetectable		 5g5gB-1tueB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 12 PHE A 463
LEU A 453
ILE A 433
ILE A 449
LEU A 627
 None
 1.05A 5h8tA-1tueA:
undetectable		 5h8tA-1tueA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		4 / 6 VAL B 191
GLN B 122
VAL B 121
TYR B 135
 None
 1.02A 5i8fA-1tueB:
undetectable		 5i8fA-1tueB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 VAL B 141
SER B 140
TRP B 138
 None
 1.06A 5jwaA-1tueB:
undetectable		 5jwaA-1tueB:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		5 / 12 LEU A 480
GLY A 494
GLY A 503
ILE A 501
PRO A 568
 None
 0.81A 5t2zB-1tueA:
undetectable		 5t2zB-1tueA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		4 / 5 LEU A 528
MET A 543
CYH A 479
CYH A 566
 None
 1.40A 5te0A-1tueA:
undetectable		 5te0A-1tueA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tue REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 GLY B 161
TRP B 189
VAL B 123
 None
 0.64A 5vuoB-1tueB:
undetectable		 5vuoB-1tueB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 1tue REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		3 / 3 TYR A 538
ALA A 546
LEU A 517
 None
 0.66A 6d9kF-1tueA:
undetectable		 6d9kF-1tueA:
15.16