SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 1tul TLP20
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 TYR A  33
GLY A  70
PHE A 102
SER A  65
 None
 1.33A 2a3cA-1tulA:
undetectable		 2a3cA-1tulA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 1tul TLP20
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 LEU A 101
SER A  65
PHE A 102
ILE A  45
 None
 0.99A 3ko0S-1tulA:
undetectable		 3ko0S-1tulA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1tul TLP20
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 VAL A  76
VAL A  47
SER A  49
 None
 0.72A 3n8xB-1tulA:
undetectable		 3n8xB-1tulA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 1tul TLP20
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 LEU A  72
ILE A  86
GLY A  41
PHE A  88
ASN A  89
 None
 1.01A 3uwlB-1tulA:
undetectable		 3uwlB-1tulA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 1tul TLP20
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 LEU A  72
ILE A  86
GLY A  41
PHE A  88
ASN A  89
 None
 1.00A 6qxsB-1tulA:
undetectable		 6qxsB-1tulA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 1tul TLP20
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 LEU A  72
ILE A  86
GLY A  41
PHE A  88
ASN A  89
 None
 1.02A 6qyaD-1tulA:
undetectable		 6qyaD-1tulA:
15.24