SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1tvd T CELL RECEPTOR
(Homo
sapiens) 		3 / 3 SER A  29
ASP A  32
ASP A  52
 None
 0.75A 2plwA-1tvdA:
undetectable		 2plwA-1tvdA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 1tvd T CELL RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A  20
LEU A  73
VAL A  74
SER A  61
VAL A 112
 None
 1.32A 3m7rA-1tvdA:
undetectable		 3m7rA-1tvdA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1tvd T CELL RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A   3
TYR A  36
GLY A 107
PHE A  90
LEU A  33
 None
 1.36A 3medA-1tvdA:
undetectable
3medB-1tvdA:
undetectable		 3medA-1tvdA:
12.15
3medB-1tvdA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 1tvd T CELL RECEPTOR
(Homo
sapiens) 		4 / 5 HIS A  64
LEU A  92
LEU A 104
ASP A 102
 None
 1.28A 4aqlA-1tvdA:
undetectable		 4aqlA-1tvdA:
14.10