SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tw9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 5 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.19A 1t88B-1tw9A:
0.0		 1t88B-1tw9A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 5 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.21A 2m56A-1tw9A:
0.0		 2m56A-1tw9A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		3 / 3 ASP A  57
TYR A   4
LYS A  28
 None
 1.01A 2othA-1tw9A:
undetectable		 2othA-1tw9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 6 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.09A 3fwgA-1tw9A:
0.0		 3fwgA-1tw9A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		5 / 12 PRO A  52
LEU A   6
TYR A   8
PRO A 202
TYR A  29
 None
 1.47A 3qlhA-1tw9A:
0.7		 3qlhA-1tw9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 6 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.11A 3wrhE-1tw9A:
0.0		 3wrhE-1tw9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 6 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.12A 3wrjE-1tw9A:
0.0		 3wrjE-1tw9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 6 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.11A 4ek1A-1tw9A:
0.0		 4ek1A-1tw9A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 8 ASN A 143
GLY A 146
HIS A 184
ILE A 153
 None
 0.94A 4fglD-1tw9A:
undetectable		 4fglD-1tw9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 5 PHE A 132
LEU A 148
VAL A 156
VAL A 164
 None
 1.14A 4l49A-1tw9A:
0.0		 4l49A-1tw9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 6 TYR A  98
ASP A 166
HIS A 163
ILE A 175
 None
 1.11A 5ih0A-1tw9A:
undetectable		 5ih0A-1tw9A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1tw9 GLUTATHIONE
S-TRANSFERASE 2
(Heligmosomoides
polygyrus) 		4 / 4 HIS A 184
VAL A 156
LEU A 148
ALA A 161
 None
 1.34A 6d8pB-1tw9A:
undetectable		 6d8pB-1tw9A:
14.80