SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1txc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		4 / 5 GLY A 139
PRO A  36
ALA A  57
ILE A  55
 2AN  A 716 (-3.7A)
2AN  A 715 (-4.4A)
2AN  A 716 (-3.4A)
2AN  A 716 (-4.2A)
 0.96A 2aofA-1txcA:
undetectable		 2aofA-1txcA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		4 / 7 VAL A 131
LEU A  97
PHE A   3
THR A 121
 None
 1.08A 2f78A-1txcA:
undetectable		 2f78A-1txcA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		4 / 7 VAL A 131
LEU A  97
PHE A   3
THR A 121
 None
 1.06A 2f78B-1txcA:
0.2		 2f78B-1txcA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 12 PHE A 119
TYR A  82
TYR A  80
PHE A 142
ILE A  55
 None
None
None
2AN  A 716 ( 4.2A)
2AN  A 716 (-4.2A)
 1.43A 3ld6B-1txcA:
undetectable		 3ld6B-1txcA:
15.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 12 ASP A  27
LYS A  53
ILE A  55
VAL A  66
TYR A  80
 None
None
2AN  A 716 (-4.2A)
2AN  A 716 (-4.0A)
None
 0.80A 4a81A-1txcA:
21.9		 4a81A-1txcA:
40.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_B_QDNB602_1
(CYTOCHROME P450 2D6)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 9 LEU A  90
PHE A 119
ALA A 135
ASP A 134
ALA A 130
 None
None
2AN  A 716 ( 4.3A)
None
None
 1.14A 4wnuB-1txcA:
undetectable		 4wnuB-1txcA:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MXB_A_ML1A220_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		5 / 9 LEU A  22
TYR A  80
TYR A  82
THR A 101
VAL A 115
 None
 0.51A 5mxbA-1txcA:
21.8		 5mxbA-1txcA:
62.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16
(Pachyrhizus
erosus) 		3 / 3 SER A 111
SER A  11
ALA A  21
 None
 0.59A 6dwnC-1txcA:
undetectable		 6dwnC-1txcA:
21.43