SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1txl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_B_NOVB444_2 (DNA GYRASE SUBUNIT B)	1txl	METAL-BINDING PROTEIN YODA (Escherichia coli)	3 / 3	ASP A 58 PHE A 163 VAL A 114	None	0.69A	1kijB-1txlA: undetectable	1kijB-1txlA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA502_1 (SALICYLIC ACID-BINDING PROTEIN 2)	1txl	METAL-BINDING PROTEIN YODA (Escherichia coli)	3 / 3	LEU A 68 HIS A 97 LYS A 93	None	1.02A	1y7iA-1txlA: undetectable	1y7iA-1txlA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_2 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	1txl	METAL-BINDING PROTEIN YODA (Escherichia coli)	4 / 5	TYR A 95 PHE A 89 HIS A 97 LEU A 73	None	1.47A	5csyB-1txlA: undetectable	5csyB-1txlA: 17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZRD_A_CUA607_0 (TYROSINASE)	1txl	METAL-BINDING PROTEIN YODA (Escherichia coli)	3 / 3	HIS A 177 HIS A 175 HIS A 166	ZN A 216 (-3.1A) ZN A 216 (-3.6A) ZN A 216 (-3.3A)	0.48A	5zrdA-1txlA: undetectable	5zrdA-1txlA: 16.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KIJ_B_NOVB444_2","DNA GYRASE SUBUNIT B","1txl","METAL-BINDING PROTEIN YODA","Escherichia coli",3,"ASP A  58;PHE A 163;VAL A 114","None","0.69A","1kijB-1txlA:undetectable","1kijB-1txlA:19.70"],["1Y7I_A_SALA502_1","SALICYLIC ACID-BINDING PROTEIN 2","1txl","METAL-BINDING PROTEIN YODA","Escherichia coli",3,"LEU A  68;HIS A  97;LYS A  93","None","1.02A","1y7iA-1txlA:undetectable","1y7iA-1txlA:19.93"],["5CSY_B_ACRB601_2","4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC\/AMYLOPLASTIC","1txl","METAL-BINDING PROTEIN YODA","Escherichia coli",4,"TYR A  95;PHE A  89;HIS A  97;LEU A  73","None","1.47A","5csyB-1txlA:undetectable","5csyB-1txlA:17.26"],["5ZRD_A_CUA607_0","TYROSINASE","1txl","METAL-BINDING PROTEIN YODA","Escherichia coli",3,"HIS A 177;HIS A 175;HIS A 166"," ZN A 216 (-3.1A); ZN A 216 (-3.6A); ZN A 216 (-3.3A)","0.48A","5zrdA-1txlA:undetectable","5zrdA-1txlA:16.54"]]