SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 LEU A 129
TRP A  48
TYR A  40
 None
 0.92A 3aicA-1tyjA:
undetectable		 3aicA-1tyjA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 LEU A 129
TRP A  48
TYR A  40
 None
 0.96A 3aicB-1tyjA:
undetectable		 3aicB-1tyjA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 LEU A 129
TRP A  48
TYR A  40
 None
 0.98A 3aicE-1tyjA:
undetectable		 3aicE-1tyjA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 LEU A 129
TRP A  48
TYR A  40
 None
 0.98A 3aicF-1tyjA:
undetectable		 3aicF-1tyjA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 LEU A 129
TRP A  48
TYR A  40
 None
 0.97A 3aicG-1tyjA:
undetectable		 3aicG-1tyjA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 LEU A 129
TRP A  48
TYR A  40
 None
 0.99A 3aicH-1tyjA:
undetectable		 3aicH-1tyjA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		4 / 7 TYR A  56
HIS A  80
LEU A 129
VAL A 111
 None
 1.10A 3jwqC-1tyjA:
undetectable		 3jwqC-1tyjA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		4 / 7 GLY A  33
PHE A  36
GLY A  90
PHE A  89
 None
 1.00A 3ko0M-1tyjA:
undetectable
3ko0P-1tyjA:
undetectable		 3ko0M-1tyjA:
21.18
3ko0P-1tyjA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		4 / 5 LEU A  21
ALA A 112
THR A   6
PHE A  36
 None
 1.36A 3vasB-1tyjA:
undetectable		 3vasB-1tyjA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		4 / 5 ILE A  23
LEU A  21
LYS A 113
ASN A  24
 None
 0.97A 4g19A-1tyjA:
undetectable		 4g19A-1tyjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		4 / 4 ILE A  23
LEU A  21
LYS A 113
ASN A  24
 None
 1.03A 4g19D-1tyjA:
0.0		 4g19D-1tyjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		5 / 12 ASN A  88
GLY A 144
PHE A 148
PHE A  36
GLY A  90
 None
 1.34A 4pevB-1tyjA:
undetectable		 4pevB-1tyjA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		3 / 3 ARG A 100
ASP A 151
TRP A 150
 None
 1.10A 4xdqA-1tyjA:
undetectable		 4xdqA-1tyjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1tyj CELLULOSOMAL
SCAFFOLDIN
(Pseudobacteroide
s
cellulosolvens) 		4 / 8 ARG A  91
ALA A  74
LEU A  92
GLY A  33
 None
EDO  A 175 (-3.6A)
None
None
 0.90A 4xk8a-1tyjA:
undetectable		 4xk8a-1tyjA:
13.34