SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 5 ARG A 289
ALA A 312
LYS A 311
GLU A 292
 None
 1.05A 1e7cA-1tz7A:
undetectable		 1e7cA-1tz7A:
20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		10 / 12 SER A  56
TYR A  58
GLN A 249
TRP A 251
HIS A 287
GLU A 333
HIS A 384
ASP A 385
ASN A 450
TRP A 459
 None
 0.60A 1eswA-1tz7A:
51.4		 1eswA-1tz7A:
44.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		10 / 12 SER A  56
TYR A  58
TRP A 251
HIS A 287
GLU A 333
HIS A 384
ASP A 385
ASN A 450
PRO A 452
TRP A 459
 None
 0.61A 1eswA-1tz7A:
51.4		 1eswA-1tz7A:
44.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 LEU A 285
LEU A 207
PRO A 208
MET A 209
 None
 1.16A 1hz4A-1tz7A:
undetectable		 1hz4A-1tz7A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TYR A  58
THR A 383
TRP A 459
MET A 449
 None
 1.41A 1uw6A-1tz7A:
undetectable
1uw6B-1tz7A:
undetectable		 1uw6A-1tz7A:
16.60
1uw6B-1tz7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TYR A  58
THR A 383
TRP A 459
MET A 449
 None
 1.45A 1uw6D-1tz7A:
undetectable
1uw6E-1tz7A:
undetectable		 1uw6D-1tz7A:
16.60
1uw6E-1tz7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TYR A  58
THR A 383
TRP A 459
MET A 449
 None
 1.43A 1uw6G-1tz7A:
undetectable
1uw6H-1tz7A:
undetectable		 1uw6G-1tz7A:
16.60
1uw6H-1tz7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TYR A  58
THR A 383
TRP A 459
MET A 449
 None
 1.44A 1uw6P-1tz7A:
undetectable
1uw6Q-1tz7A:
undetectable		 1uw6P-1tz7A:
16.60
1uw6Q-1tz7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TRP A 459
MET A 449
TYR A  58
THR A 383
 None
 1.42A 1uw6P-1tz7A:
undetectable
1uw6T-1tz7A:
0.0		 1uw6P-1tz7A:
16.60
1uw6T-1tz7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		3 / 3 ASP A 242
GLU A 333
ARG A 343
 None
 0.74A 1wopA-1tz7A:
undetectable		 1wopA-1tz7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 7 TYR A  58
ASP A 286
TYR A 380
HIS A 384
 None
 1.48A 2bytA-1tz7A:
0.0		 2bytA-1tz7A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 7 TYR A  58
ASP A 286
TYR A 380
HIS A 384
 None
 1.48A 2bytD-1tz7A:
0.0		 2bytD-1tz7A:
20.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		10 / 11 SER A  56
TYR A  58
GLN A 249
TRP A 251
ASP A 286
HIS A 384
ASP A 385
ASN A 450
PRO A 452
TRP A 459
 None
 0.44A 2owcA-1tz7A:
52.5		 2owcA-1tz7A:
46.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		10 / 11 SER A  56
TYR A  58
GLN A 249
TRP A 251
ASP A 286
HIS A 384
ASP A 385
ASN A 450
PRO A 452
TRP A 459
 None
 0.64A 2owwA-1tz7A:
52.4		 2owwA-1tz7A:
46.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_D_LEUD1883_0
(AMINOACYL-TRNA
SYNTHETASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 5 TYR A  58
ASP A 286
TYR A 380
HIS A 384
 None
 1.40A 2v0gD-1tz7A:
0.0		 2v0gD-1tz7A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 7 ILE A 422
ILE A 463
LEU A 477
LEU A  33
 None
 0.89A 3adxA-1tz7A:
undetectable		 3adxA-1tz7A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 GLN A 249
GLY A 248
HIS A 287
TRP A 251
 None
 1.46A 3ai8B-1tz7A:
undetectable		 3ai8B-1tz7A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 9 VAL A 378
ILE A 331
ILE A 203
ALA A   4
ILE A 434
 None
 1.04A 3el0B-1tz7A:
undetectable		 3el0B-1tz7A:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 LEU A 321
SER A 323
PHE A 325
ILE A 270
 None
 0.96A 3ko0B-1tz7A:
undetectable		 3ko0B-1tz7A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 LEU A 321
SER A 323
PHE A 325
ILE A 270
 None
 0.96A 3ko0S-1tz7A:
0.3		 3ko0S-1tz7A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 ASN A 445
GLN A 436
SER A 382
ASN A 395
 None
 0.77A 3kp2A-1tz7A:
undetectable
3kp2B-1tz7A:
2.0		 3kp2A-1tz7A:
16.47
3kp2B-1tz7A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 SER A  62
GLN A 182
PHE A 186
HIS A 275
 None
 1.19A 3lskB-1tz7A:
undetectable		 3lskB-1tz7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 SER A  62
GLN A 182
PHE A 186
HIS A 275
 None
 1.20A 3lskD-1tz7A:
0.5		 3lskD-1tz7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		3 / 3 PRO A  48
THR A  49
LEU A  70
 None
 0.79A 3ttrA-1tz7A:
undetectable		 3ttrA-1tz7A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_C_T1CC401_1
(TETX2 PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 11 ASP A 385
ASN A  47
HIS A   9
SER A  60
PRO A 208
 None
 1.39A 3v3oC-1tz7A:
undetectable		 3v3oC-1tz7A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 4 LEU A 335
ILE A 389
TYR A 362
TYR A 380
 None
 1.27A 3vt7A-1tz7A:
0.0		 3vt7A-1tz7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 10 ALA A  26
GLY A  20
LEU A  46
LEU A  22
ASP A  72
 None
 1.14A 3wdmD-1tz7A:
undetectable		 3wdmD-1tz7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TYR A  58
THR A 383
TRP A 459
MET A 449
 None
 1.48A 3wipD-1tz7A:
undetectable
3wipE-1tz7A:
undetectable		 3wipD-1tz7A:
17.00
3wipE-1tz7A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TYR A 210
TYR A 294
TRP A 251
ARG A 308
 None
 1.44A 3wipD-1tz7A:
undetectable
3wipE-1tz7A:
undetectable		 3wipD-1tz7A:
17.00
3wipE-1tz7A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 4 LEU A 317
ILE A 351
GLY A 314
PHE A 288
 None
 0.96A 4dc3A-1tz7A:
undetectable		 4dc3A-1tz7A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 6 LEU A  46
LEU A  70
ILE A  19
THR A  49
 None
 0.93A 4do3B-1tz7A:
undetectable		 4do3B-1tz7A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 GLU A 420
ASP A 439
ILE A 422
ILE A 474
 None
 0.89A 4kttD-1tz7A:
undetectable		 4kttD-1tz7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 11 ALA A 216
SER A 129
PHE A 124
LEU A 125
THR A 220
 None
 1.44A 4kyaE-1tz7A:
undetectable		 4kyaE-1tz7A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 11 SER A  12
LEU A   7
ASP A 439
LEU A 443
LEU A   8
 None
 1.43A 4or0A-1tz7A:
0.3		 4or0A-1tz7A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		3 / 3 ALA A 293
TRP A 309
VAL A 310
 None
 0.34A 4w9nC-1tz7A:
undetectable		 4w9nC-1tz7A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 7 VAL A 356
ILE A 357
LEU A 478
LEU A 426
 None
 1.02A 4xo7A-1tz7A:
8.1		 4xo7A-1tz7A:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		9 / 12 GLN A 249
ARG A 284
ASP A 286
GLU A 333
GLY A 336
PHE A 359
HIS A 368
HIS A 384
ASP A 385
 None
 0.86A 5csyB-1tz7A:
49.4		 5csyB-1tz7A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		9 / 12 GLN A 249
TRP A 251
ASP A 286
GLU A 333
GLY A 336
PHE A 359
HIS A 368
HIS A 384
ASP A 385
 None
 0.81A 5csyB-1tz7A:
49.4		 5csyB-1tz7A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 5 TYR A  58
HIS A 287
LEU A 335
PRO A 452
 None
 0.50A 5csyB-1tz7A:
49.4		 5csyB-1tz7A:
38.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 8 TRP A 258
TRP A 269
HIS A 287
THR A 348
 None
 1.44A 5hqaA-1tz7A:
6.4		 5hqaA-1tz7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 5 PHE A 282
PHE A 280
LEU A 283
LEU A   7
 None
 0.94A 5veuH-1tz7A:
undetectable		 5veuH-1tz7A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 12 ALA A  95
ARG A 462
LEU A  96
VAL A 100
ASP A  21
 None
 1.21A 5x24A-1tz7A:
undetectable		 5x24A-1tz7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		3 / 3 TYR A 451
PRO A 387
LEU A 386
 None
 0.82A 6beoA-1tz7A:
undetectable		 6beoA-1tz7A:
4.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		5 / 12 LEU A  13
GLY A  20
LYS A 191
VAL A 184
ILE A  71
 None
 1.26A 6bxnB-1tz7A:
undetectable		 6bxnB-1tz7A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 7 GLU A 420
ASP A 439
ILE A 422
ILE A 474
 None
 0.84A 6fbnA-1tz7A:
undetectable		 6fbnA-1tz7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		3 / 3 ARG A 289
PHE A 288
GLY A 290
 None
 0.63A 6fgdA-1tz7A:
undetectable		 6fgdA-1tz7A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_1
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 1tz7 4-ALPHA-GLUCANOTRANS
FERASE
(Aquifex
aeolicus) 		4 / 5 ASN A 445
GLN A 436
HIS A 384
TYR A  58
 None
 1.30A 6hlpA-1tz7A:
0.1		 6hlpA-1tz7A:
20.72