SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u08'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 8 ILE A 365
HIS A 345
LEU A 383
VAL A 324
 None
 0.89A 1fslA-1u08A:
undetectable		 1fslA-1u08A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 8 ILE A 365
HIS A 345
LEU A 383
VAL A 324
 None
 0.82A 1fslB-1u08A:
0.0		 1fslB-1u08A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 THR A 171
SER A 201
LEU A 224
VAL A 199
ALA A 187
 None
 1.23A 1q23H-1u08A:
undetectable
1q23I-1u08A:
undetectable		 1q23H-1u08A:
20.78
1q23I-1u08A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 7 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.08A 1rxcF-1u08A:
undetectable		 1rxcF-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 7 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.08A 1rxcL-1u08A:
undetectable		 1rxcL-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 VAL A 112
CYH A 248
ALA A 103
LEU A 104
ALA A 250
 None
 1.17A 1sa1A-1u08A:
undetectable
1sa1B-1u08A:
undetectable		 1sa1A-1u08A:
21.07
1sa1B-1u08A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 7 ALA A 131
TYR A 128
ILE A 108
ILE A 200
ASP A 202
 None
None
None
None
PLP  A 400 (-2.9A)
 1.33A 1upfB-1u08A:
4.1		 1upfB-1u08A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 8 ASP A 325
SER A 327
TYR A 326
HIS A 362
 None
 1.20A 2bteA-1u08A:
undetectable		 2bteA-1u08A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 8 ILE A 108
ILE A 200
ILE A 197
ILE A 132
ASN A 170
 None
None
None
None
PLP  A 400 (-3.1A)
 1.22A 2nniA-1u08A:
undetectable		 2nniA-1u08A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 LEU A 104
VAL A 261
ILE A 200
ALA A 110
LEU A 166
 None
 1.09A 2q72A-1u08A:
0.0		 2q72A-1u08A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 LEU A 104
VAL A 261
ILE A 200
ALA A 110
LEU A 166
 None
 1.09A 2qb4A-1u08A:
0.0		 2qb4A-1u08A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 10 ALA A 349
GLN A 385
LEU A 386
LEU A 341
LEU A 383
 None
 1.17A 2riwA-1u08A:
undetectable
2riwB-1u08A:
undetectable		 2riwA-1u08A:
22.25
2riwB-1u08A:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 8 LEU A 306
LEU A 383
ILE A 365
VAL A 347
ILE A  33
 None
 1.46A 2uxpA-1u08A:
undetectable		 2uxpA-1u08A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_A_PXLA1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 LEU A 104
TYR A 125
ASP A 202
VAL A 204
LYS A 236
 None
PLP  A 400 (-3.6A)
PLP  A 400 (-2.9A)
PLP  A 400 (-4.6A)
PLP  A 400 (-2.7A)
 0.98A 2z9wA-1u08A:
22.8		 2z9wA-1u08A:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_B_PXLB1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 LEU A 104
TYR A 125
ASP A 202
VAL A 204
LYS A 236
 None
PLP  A 400 (-3.6A)
PLP  A 400 (-2.9A)
PLP  A 400 (-4.6A)
PLP  A 400 (-2.7A)
 0.92A 2z9wB-1u08A:
22.7		 2z9wB-1u08A:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9X_B_PXLB2503_1
(ASPARTATE
AMINOTRANSFERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 LEU A 104
TYR A 125
ASP A 202
VAL A 204
LYS A 236
 None
PLP  A 400 (-3.6A)
PLP  A 400 (-2.9A)
PLP  A 400 (-4.6A)
PLP  A 400 (-2.7A)
 1.32A 2z9xB-1u08A:
22.8		 2z9xB-1u08A:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 LEU A 219
VAL A 218
SER A 217
SER A 232
LEU A 166
 None
 1.33A 2zlcA-1u08A:
undetectable		 2zlcA-1u08A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 ALA A 228
ARG A 225
ILE A 197
ALA A 193
PHE A 185
 None
 1.21A 3axtA-1u08A:
5.2		 3axtA-1u08A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 TYR A  86
ALA A 220
LEU A 219
ALA A 228
 None
 0.88A 3b6hA-1u08A:
undetectable		 3b6hA-1u08A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 SER A 161
ILE A 119
PHE A 198
GLU A 117
ASP A 116
 None
 1.36A 3ko0A-1u08A:
undetectable
3ko0B-1u08A:
0.0
3ko0C-1u08A:
undetectable
3ko0D-1u08A:
undetectable		 3ko0A-1u08A:
13.17
3ko0B-1u08A:
13.17
3ko0C-1u08A:
13.17
3ko0D-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 GLU A 117
ASP A 116
SER A 161
ILE A 119
PHE A 198
 None
 1.43A 3ko0C-1u08A:
undetectable
3ko0D-1u08A:
undetectable
3ko0E-1u08A:
0.0
3ko0F-1u08A:
undetectable		 3ko0C-1u08A:
13.17
3ko0D-1u08A:
13.17
3ko0E-1u08A:
13.17
3ko0F-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 SER A 161
ILE A 119
PHE A 198
GLU A 117
ASP A 116
 None
 1.39A 3ko0C-1u08A:
undetectable
3ko0D-1u08A:
undetectable
3ko0E-1u08A:
0.0
3ko0F-1u08A:
undetectable		 3ko0C-1u08A:
13.17
3ko0D-1u08A:
13.17
3ko0E-1u08A:
13.17
3ko0F-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 GLU A 117
ASP A 116
SER A 161
ILE A 119
PHE A 198
 None
 1.41A 3ko0E-1u08A:
0.0
3ko0F-1u08A:
undetectable
3ko0G-1u08A:
undetectable
3ko0H-1u08A:
undetectable		 3ko0E-1u08A:
13.17
3ko0F-1u08A:
13.17
3ko0G-1u08A:
13.17
3ko0H-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 10 SER A 161
ILE A 119
PHE A 198
GLU A 117
ASP A 116
 None
 1.35A 3ko0E-1u08A:
0.0
3ko0F-1u08A:
undetectable
3ko0G-1u08A:
undetectable
3ko0H-1u08A:
undetectable		 3ko0E-1u08A:
13.17
3ko0F-1u08A:
13.17
3ko0G-1u08A:
13.17
3ko0H-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 GLU A 117
ASP A 116
SER A 161
ILE A 119
PHE A 198
 None
 1.38A 3ko0G-1u08A:
undetectable
3ko0H-1u08A:
undetectable
3ko0I-1u08A:
0.0
3ko0J-1u08A:
0.0		 3ko0G-1u08A:
13.17
3ko0H-1u08A:
13.17
3ko0I-1u08A:
13.17
3ko0J-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 GLU A 117
ASP A 116
SER A 161
ILE A 119
PHE A 198
 None
 1.34A 3ko0K-1u08A:
0.0
3ko0L-1u08A:
undetectable
3ko0M-1u08A:
0.0
3ko0N-1u08A:
undetectable		 3ko0K-1u08A:
13.17
3ko0L-1u08A:
13.17
3ko0M-1u08A:
13.17
3ko0N-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 SER A 161
ILE A 119
PHE A 198
GLU A 117
ASP A 116
 None
 1.42A 3ko0O-1u08A:
undetectable
3ko0P-1u08A:
undetectable
3ko0Q-1u08A:
0.0
3ko0R-1u08A:
0.0		 3ko0O-1u08A:
13.17
3ko0P-1u08A:
13.17
3ko0Q-1u08A:
13.17
3ko0R-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 10 SER A 161
ILE A 119
PHE A 198
GLU A 117
ASP A 116
 None
 1.40A 3ko0O-1u08A:
undetectable
3ko0P-1u08A:
undetectable
3ko0Q-1u08A:
0.0
3ko0R-1u08A:
0.0		 3ko0O-1u08A:
13.17
3ko0P-1u08A:
13.17
3ko0Q-1u08A:
13.17
3ko0R-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 GLU A 117
ASP A 116
SER A 161
ILE A 119
PHE A 198
 None
 1.31A 3ko0Q-1u08A:
0.0
3ko0R-1u08A:
0.0
3ko0S-1u08A:
0.0
3ko0T-1u08A:
undetectable		 3ko0Q-1u08A:
13.17
3ko0R-1u08A:
13.17
3ko0S-1u08A:
13.17
3ko0T-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 11 GLU A 117
ASP A 116
SER A 161
ILE A 119
PHE A 198
 None
 1.34A 3ko0Q-1u08A:
0.0
3ko0R-1u08A:
0.0
3ko0S-1u08A:
0.0
3ko0T-1u08A:
undetectable		 3ko0Q-1u08A:
13.17
3ko0R-1u08A:
13.17
3ko0S-1u08A:
13.17
3ko0T-1u08A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.08A 3kvvA-1u08A:
undetectable		 3kvvA-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.08A 3kvvB-1u08A:
undetectable		 3kvvB-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.09A 3kvvC-1u08A:
undetectable		 3kvvC-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.08A 3kvvD-1u08A:
undetectable		 3kvvD-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.10A 3kvvE-1u08A:
undetectable		 3kvvE-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.08A 3kvvF-1u08A:
undetectable		 3kvvF-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 LEU A 169
VAL A 199
PHE A 198
LEU A 219
VAL A 218
 None
 1.28A 3sp9B-1u08A:
undetectable		 3sp9B-1u08A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 7 ASN A 270
ALA A 273
PRO A 272
ALA A  64
 None
 1.08A 3twpA-1u08A:
undetectable		 3twpA-1u08A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 7 ASN A 270
ALA A 273
PRO A 272
ALA A  64
 None
 1.07A 3twpB-1u08A:
undetectable		 3twpB-1u08A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 7 ASN A 270
ALA A 273
PRO A 272
ALA A  64
 None
 1.06A 3twpC-1u08A:
undetectable		 3twpC-1u08A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 5 ASN A 270
ALA A 273
PRO A 272
ALA A  64
 None
 1.06A 3twpD-1u08A:
undetectable		 3twpD-1u08A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 THR A 171
SER A 201
LEU A 224
VAL A 199
ALA A 187
 None
 1.27A 3u9fD-1u08A:
0.0
3u9fE-1u08A:
0.0		 3u9fD-1u08A:
20.78
3u9fE-1u08A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 THR A 171
SER A 201
LEU A 224
VAL A 199
ALA A 187
 None
 1.34A 3u9fG-1u08A:
1.5
3u9fH-1u08A:
0.0		 3u9fG-1u08A:
20.78
3u9fH-1u08A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 12 ALA A 103
VAL A  96
THR A 237
ILE A  76
PHE A 234
 None
 1.25A 4c49A-1u08A:
undetectable		 4c49A-1u08A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 7 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.04A 4e1vB-1u08A:
undetectable		 4e1vB-1u08A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 6 GLY A 346
GLN A 385
ILE A  33
VAL A 347
 None
 1.13A 4e1vF-1u08A:
undetectable		 4e1vF-1u08A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		3 / 3 LEU A 275
ARG A  51
ARG A 282
 None
 0.94A 4yiaB-1u08A:
0.0		 4yiaB-1u08A:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		4 / 8 LEU A 322
LEU A  35
ALA A 349
LEU A 341
 None
 0.85A 5y7pE-1u08A:
undetectable		 5y7pE-1u08A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL
(Escherichia
coli) 		5 / 10 SER A 217
GLU A 206
SER A 232
GLU A 203
TYR A 288
 None
 1.48A 6c5uA-1u08A:
0.0		 6c5uA-1u08A:
21.05