SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 GLN A 438
ASP A 443
TRP A 331
TYR A 485
 None
 1.12A 2xz5A-1u0jA:
undetectable
2xz5C-1u0jA:
undetectable		 2xz5A-1u0jA:
22.22
2xz5C-1u0jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6D_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 PHE A 366
VAL A 418
TRP A 377
PRO A 365
 None
 1.48A 3n6dA-1u0jA:
0.0
3n6dB-1u0jA:
0.0		 3n6dA-1u0jA:
20.73
3n6dB-1u0jA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		4 / 5 PHE A 316
LEU A 450
GLY A 339
ILE A 347
 None
None
ADP  A 491 (-3.3A)
None
 0.88A 3wrkA-1u0jA:
undetectable		 3wrkA-1u0jA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA6_0
(VAL-GRAMICIDIN A)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		4 / 4 ALA A 344
VAL A 418
TRP A 319
TRP A 377
 None
 1.32A 3zq8A-1u0jA:
undetectable
3zq8B-1u0jA:
undetectable		 3zq8A-1u0jA:
4.88
3zq8B-1u0jA:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 HIS A 437
VAL A 418
LEU A 394
 None
 0.70A 4m2vA-1u0jA:
undetectable		 4m2vA-1u0jA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		4 / 5 PHE A 316
LEU A 450
GLY A 339
ILE A 347
 None
None
ADP  A 491 (-3.3A)
None
 1.01A 5ik1A-1u0jA:
0.0		 5ik1A-1u0jA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 LYS A 372
LEU A 284
ILE A 417
 None
 0.65A 5kc0A-1u0jA:
undetectable		 5kc0A-1u0jA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 THR A 321
PRO A 281
ASP A 282
 None
 0.85A 5l8dB-1u0jA:
0.7		 5l8dB-1u0jA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 THR A 321
PRO A 281
ASP A 282
 None
 0.85A 5mwuB-1u0jA:
0.7		 5mwuB-1u0jA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1u0j DNA REPLICATION
PROTEIN
(Adeno-associated
dependoparvoviru
s
A) 		5 / 9 LEU A 284
VAL A 466
ILE A 330
PHE A 316
ILE A 417
 None
 1.15A 5yf9X-1u0jA:
undetectable		 5yf9X-1u0jA:
14.39