SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 11 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.33A 1jb0B-1u0kA:
undetectable		 1jb0B-1u0kA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  75
ILE A  63
ILE A  48
ALA A  81
GLU A  46
 None
 1.19A 1ki7A-1u0kA:
undetectable		 1ki7A-1u0kA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  75
ILE A  63
ILE A  48
ALA A  81
GLU A  46
 None
 1.24A 1ki7B-1u0kA:
undetectable		 1ki7B-1u0kA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 166
VAL A 158
THR A 160
VAL A 266
 None
 0.71A 1o76B-1u0kA:
0.0		 1o76B-1u0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 105
ALA A 106
HIS A  95
 None
 0.77A 1q23C-1u0kA:
undetectable		 1q23C-1u0kA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 105
ALA A 106
HIS A  95
 None
 0.66A 1q23H-1u0kA:
undetectable		 1q23H-1u0kA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 105
ALA A 106
HIS A  95
 None
 0.69A 1q23G-1u0kA:
undetectable		 1q23G-1u0kA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 105
ALA A 106
HIS A  95
 None
 0.63A 1q23J-1u0kA:
undetectable		 1q23J-1u0kA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		6 / 10 LEU A   8
ALA A  81
LEU A  98
LEU A  50
VAL A  23
ILE A  63
 None
 1.39A 2w9hA-1u0kA:
undetectable		 2w9hA-1u0kA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 10 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.36A 2wscB-1u0kA:
undetectable		 2wscB-1u0kA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 10 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.36A 2wseB-1u0kA:
undetectable		 2wseB-1u0kA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 VAL A 243
VAL A 268
GLY A 269
GLY A 270
ALA A 223
 None
 0.90A 2z0yA-1u0kA:
undetectable		 2z0yA-1u0kA:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 166
VAL A 158
THR A 160
VAL A 266
 None
 0.93A 2zaxA-1u0kA:
undetectable		 2zaxA-1u0kA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 168
LEU A 198
ARG A 203
 None
 0.75A 3aqiA-1u0kA:
undetectable		 3aqiA-1u0kA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 166
VAL A 158
THR A 160
VAL A 266
 None
 0.92A 3fwgB-1u0kA:
undetectable		 3fwgB-1u0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 166
VAL A 158
THR A 160
VAL A 266
 None
 0.95A 3fwiA-1u0kA:
undetectable		 3fwiA-1u0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 10 VAL A  10
GLY A  79
VAL A 217
ILE A  48
GLY A  20
 None
 1.32A 3km6A-1u0kA:
undetectable		 3km6A-1u0kA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2W_A_ELVA397_1
(INTEGRASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 201
ASP A 199
TYR A 196
PRO A 168
 None
 1.36A 3l2wA-1u0kA:
0.2		 3l2wA-1u0kA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 PRO A  76
SER A 221
ASN A  19
 None
 0.86A 3lslG-1u0kA:
undetectable		 3lslG-1u0kA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  48
GLY A  79
ALA A  80
LEU A  84
LEU A  87
 None
 0.85A 3n8yB-1u0kA:
0.0		 3n8yB-1u0kA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 11 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.33A 3pcqB-1u0kA:
undetectable		 3pcqB-1u0kA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 257
GLY A 270
PRO A 241
ARG A 108
 None
 0.86A 3s3nA-1u0kA:
undetectable		 3s3nA-1u0kA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.35A 4kt0B-1u0kA:
0.0		 4kt0B-1u0kA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.28A 4l6v2-1u0kA:
undetectable		 4l6v2-1u0kA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.40A 4l6va-1u0kA:
undetectable
4l6vf-1u0kA:
0.0		 4l6va-1u0kA:
18.28
4l6vf-1u0kA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.34A 4l6vB-1u0kA:
0.0		 4l6vB-1u0kA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  74
ALA A  73
VAL A 105
LEU A 107
ILE A  48
 None
 1.23A 4pd9A-1u0kA:
undetectable		 4pd9A-1u0kA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 PRO A  15
LEU A  16
GLN A   7
 None
 0.73A 4pevB-1u0kA:
undetectable		 4pevB-1u0kA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 GLN A  94
HIS A  85
ARG A 111
 None
 1.11A 4qyqA-1u0kA:
undetectable		 4qyqA-1u0kA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 GLN A  94
HIS A  85
ARG A 111
 None
 1.07A 4qyqB-1u0kA:
undetectable		 4qyqB-1u0kA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.30A 4rkuB-1u0kA:
undetectable		 4rkuB-1u0kA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 10 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.30A 4xk8B-1u0kA:
undetectable		 4xk8B-1u0kA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 9 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.28A 4y28B-1u0kA:
undetectable		 4y28B-1u0kA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 148
SER A 146
ARG A 176
 None
 0.76A 5b2qA-1u0kA:
undetectable		 5b2qA-1u0kA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1u0k GENE PRODUCT PA4716
(Pseudomonas
aeruginosa) 		5 / 12 TRP A   6
SER A 109
TRP A  96
ALA A  80
LEU A  83
 None
 1.31A 5oy02-1u0kA:
undetectable		 5oy02-1u0kA:
14.45