SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		4 / 6 PHE A 225
ILE A 230
LYS A 107
ALA A 105
 None
 1.22A 1hk2A-1u0lA:
undetectable		 1hk2A-1u0lA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		4 / 6 LEU A 210
TYR A 218
ILE A 165
GLY A   7
 None
 0.89A 2du8A-1u0lA:
undetectable		 2du8A-1u0lA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		4 / 6 LEU A 210
TYR A 218
ILE A 165
GLY A   7
 None
 0.89A 2du8B-1u0lA:
undetectable		 2du8B-1u0lA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 ASN A 117
VAL A  85
ILE A 183
THR A 146
LEU A 157
 GDP  A 299 (-3.1A)
None
None
None
None
 1.37A 3bexC-1u0lA:
1.4
3bexD-1u0lA:
undetectable		 3bexC-1u0lA:
25.08
3bexD-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 THR A 146
LEU A 157
ASN A 117
VAL A  85
ILE A 183
 None
None
GDP  A 299 (-3.1A)
None
None
 1.36A 3bexE-1u0lA:
undetectable
3bexF-1u0lA:
1.6		 3bexE-1u0lA:
25.08
3bexF-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 ASN A 117
VAL A  85
ILE A 183
THR A 146
LEU A 157
 GDP  A 299 (-3.1A)
None
None
None
None
 1.38A 3bf1A-1u0lA:
undetectable
3bf1B-1u0lA:
undetectable		 3bf1A-1u0lA:
25.08
3bf1B-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 ASN A 117
VAL A  85
ILE A 183
THR A 146
LEU A 157
 GDP  A 299 (-3.1A)
None
None
None
None
 1.34A 3bf1C-1u0lA:
1.6
3bf1D-1u0lA:
undetectable		 3bf1C-1u0lA:
25.08
3bf1D-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 THR A 146
LEU A 157
ASN A 117
VAL A  85
ILE A 183
 None
None
GDP  A 299 (-3.1A)
None
None
 1.38A 3bf1C-1u0lA:
1.6
3bf1D-1u0lA:
undetectable		 3bf1C-1u0lA:
25.08
3bf1D-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 ASN A 117
VAL A  85
ILE A 183
THR A 146
LEU A 157
 GDP  A 299 (-3.1A)
None
None
None
None
 1.36A 3bf1E-1u0lA:
undetectable
3bf1F-1u0lA:
undetectable		 3bf1E-1u0lA:
25.08
3bf1F-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 THR A 146
LEU A 157
ASN A 117
VAL A  85
ILE A 183
 None
None
GDP  A 299 (-3.1A)
None
None
 1.37A 3bf1E-1u0lA:
undetectable
3bf1F-1u0lA:
undetectable		 3bf1E-1u0lA:
25.08
3bf1F-1u0lA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		4 / 7 ARG A  67
ALA A  77
VAL A  49
VAL A   9
 None
 0.86A 3o14A-1u0lA:
undetectable		 3o14A-1u0lA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		3 / 3 PRO A  53
ASP A  54
GLU A  62
 None
 0.88A 3v4tC-1u0lA:
undetectable		 3v4tC-1u0lA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 9 GLU A  22
GLY A   7
VAL A  49
GLU A  55
GLY A  59
 None
 1.44A 4fimA-1u0lA:
undetectable		 4fimA-1u0lA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1u0l PROBABLE GTPASE ENGC
(Thermotoga
maritima) 		5 / 11 ILE A 154
ALA A 148
LEU A 180
ILE A  83
LEU A 161
 None
GDP  A 299 (-3.5A)
None
None
None
 1.20A 4qlfA-1u0lA:
undetectable		 4qlfA-1u0lA:
18.60