SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 12 LEU D  36
LEU D  60
LEU D  82
LEU D  25
THR D  33
 None
 1.30A 1a28B-1u0nD:
undetectable		 1a28B-1u0nD:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		3 / 3 ALA D 244
VAL D 256
TRP D 207
 None
 0.91A 1c4dC-1u0nD:
undetectable
1c4dD-1u0nD:
undetectable		 1c4dC-1u0nD:
4.42
1c4dD-1u0nD:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 7 LEU D 144
THR D 147
GLY D 170
LEU D 168
 None
 0.91A 1gtiB-1u0nD:
undetectable		 1gtiB-1u0nD:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 4 LEU D 131
SER D 108
TYR D 130
LEU D 129
 None
 1.28A 1xz1A-1u0nD:
undetectable		 1xz1A-1u0nD:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 4 LEU D 131
SER D 108
TYR D 130
LEU D 129
 None
 1.29A 1xz3A-1u0nD:
undetectable		 1xz3A-1u0nD:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 12 LEU D  36
LEU D  60
LEU D  82
LEU D  25
THR D  33
 None
 1.24A 1zucB-1u0nD:
undetectable		 1zucB-1u0nD:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 PRO D  26
PRO D  27
THR D  33
LEU D  38
VAL D  15
 None
 1.28A 2uvnB-1u0nD:
undetectable		 2uvnB-1u0nD:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 12 TYR D 215
LEU D 197
LEU D 168
ILE D 187
PHE D 216
 None
 1.25A 2weyA-1u0nD:
undetectable		 2weyA-1u0nD:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 8 LEU D  92
LEU D 105
SER D  85
ASN D 110
 None
 1.04A 3lm8B-1u0nD:
undetectable
3lm8D-1u0nD:
undetectable		 3lm8B-1u0nD:
21.17
3lm8D-1u0nD:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 5 PHE D  46
ALA D  49
THR D  98
LEU D  70
 None
 1.15A 3t3zC-1u0nD:
undetectable		 3t3zC-1u0nD:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 LEU D  60
LEU D  36
LEU D  51
ALA D  24
LEU D  25
 None
 1.11A 4wg0H-1u0nD:
undetectable
4wg0I-1u0nD:
undetectable
4wg0J-1u0nD:
undetectable		 4wg0H-1u0nD:
5.38
4wg0I-1u0nD:
5.38
4wg0J-1u0nD:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 ALA D  24
LEU D  25
LEU D  51
LEU D  60
LEU D  36
 None
 1.11A 4wg0G-1u0nD:
undetectable
4wg0H-1u0nD:
undetectable
4wg0I-1u0nD:
undetectable		 4wg0G-1u0nD:
5.38
4wg0H-1u0nD:
5.38
4wg0I-1u0nD:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 LEU D  60
LEU D  36
LEU D  51
ALA D  24
LEU D  25
 None
 1.08A 4wg0J-1u0nD:
undetectable
4wg0K-1u0nD:
undetectable
4wg0L-1u0nD:
undetectable		 4wg0J-1u0nD:
5.38
4wg0K-1u0nD:
5.38
4wg0L-1u0nD:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 ALA D  24
LEU D  25
LEU D  51
LEU D  60
LEU D  36
 None
 1.10A 4wg0I-1u0nD:
undetectable
4wg0J-1u0nD:
undetectable
4wg0K-1u0nD:
undetectable		 4wg0I-1u0nD:
5.38
4wg0J-1u0nD:
5.38
4wg0K-1u0nD:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 LEU D  29
LEU D  25
ASN D  41
LEU D  38
LEU D  36
 None
 1.08A 4wg0K-1u0nD:
undetectable
4wg0L-1u0nD:
undetectable
4wg0M-1u0nD:
undetectable		 4wg0K-1u0nD:
5.38
4wg0L-1u0nD:
5.38
4wg0M-1u0nD:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 10 SER D  39
LEU D  76
LEU D  48
LEU D  62
LEU D  95
 None
 1.21A 4yiaA-1u0nD:
undetectable		 4yiaA-1u0nD:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 8 LEU D 131
LEU D 136
LEU D 139
LEU D 143
ALA D 119
 None
 1.17A 4z90A-1u0nD:
undetectable
4z90B-1u0nD:
undetectable
4z90C-1u0nD:
undetectable
4z90D-1u0nD:
undetectable
4z90E-1u0nD:
undetectable		 4z90A-1u0nD:
21.55
4z90B-1u0nD:
21.55
4z90C-1u0nD:
21.55
4z90D-1u0nD:
21.55
4z90E-1u0nD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 10 LEU D 143
LEU D 144
LEU D 153
LEU D 155
LEU D 139
 None
 1.05A 4z91A-1u0nD:
0.0
4z91B-1u0nD:
0.0
4z91C-1u0nD:
0.0
4z91D-1u0nD:
0.0
4z91E-1u0nD:
0.0		 4z91A-1u0nD:
21.55
4z91B-1u0nD:
21.55
4z91C-1u0nD:
21.55
4z91D-1u0nD:
21.55
4z91E-1u0nD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 10 LEU D 155
LEU D 139
LEU D 143
LEU D 144
LEU D 153
 None
 1.02A 4z91A-1u0nD:
0.0
4z91B-1u0nD:
0.0
4z91C-1u0nD:
0.0
4z91D-1u0nD:
0.0
4z91E-1u0nD:
0.0		 4z91A-1u0nD:
21.55
4z91B-1u0nD:
21.55
4z91C-1u0nD:
21.55
4z91D-1u0nD:
21.55
4z91E-1u0nD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 8 ASP D 222
ASN D 223
ALA D 224
VAL D 227
 None
 0.90A 4zbqA-1u0nD:
undetectable		 4zbqA-1u0nD:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 11 LEU D 184
LEU D 129
LEU D 167
LEU D 163
LEU D 144
 None
 1.01A 4zowA-1u0nD:
undetectable		 4zowA-1u0nD:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		3 / 3 ASN D 205
LEU D 220
PHE D 201
 None
 0.83A 5dsgA-1u0nD:
undetectable		 5dsgA-1u0nD:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 12 LEU D 163
PRO D 146
LEU D 120
ASN D 169
LEU D 139
 None
 1.43A 5emlA-1u0nD:
undetectable		 5emlA-1u0nD:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		5 / 12 PRO D 164
LEU D 163
PRO D 146
LEU D 120
ASN D 169
 None
 1.16A 5emlA-1u0nD:
undetectable		 5emlA-1u0nD:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		3 / 3 HIS D  37
ASN D  61
LEU D  60
 None
 0.71A 6f7lB-1u0nD:
undetectable		 6f7lB-1u0nD:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 6 LEU D 120
ALA D 119
LEU D 153
ASN D 158
 None
 0.84A 6f88B-1u0nD:
0.0		 6f88B-1u0nD:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens) 		4 / 7 LEU D 167
LEU D 153
LEU D 150
LEU D 115
 None
 0.72A 6g9bA-1u0nD:
0.0
6g9bB-1u0nD:
0.0		 6g9bA-1u0nD:
17.62
6g9bB-1u0nD:
17.50