SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 GLY A 136
GLY A 139
LEU A 133
GLY A 114
THR A  36
 None
 1.15A 1jg2A-1u11A:
undetectable		 1jg2A-1u11A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 9 THR A  36
GLY A 136
GLY A  85
SER A 117
GLY A  83
 None
None
CIT  A1001 (-4.3A)
None
None
 1.32A 1jhoA-1u11A:
4.8		 1jhoA-1u11A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 8 THR A  36
GLY A 136
GLY A  85
SER A 117
GLY A  83
 None
None
CIT  A1001 (-4.3A)
None
None
 1.33A 1jhqA-1u11A:
undetectable		 1jhqA-1u11A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 8 THR A  36
GLY A 136
GLY A  85
SER A 117
GLY A  83
 None
None
CIT  A1001 (-4.3A)
None
None
 1.35A 1jhvA-1u11A:
4.5		 1jhvA-1u11A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 9 THR A  36
GLY A 136
GLY A  85
SER A 117
GLY A  83
 None
None
CIT  A1001 (-4.3A)
None
None
 1.34A 1jhyA-1u11A:
4.8		 1jhyA-1u11A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 GLY A  85
ALA A  84
ASP A  33
GLY A 136
ILE A 135
 CIT  A1001 (-4.3A)
CIT  A1001 (-3.8A)
CIT  A1001 (-2.9A)
None
None
 1.08A 2b7zA-1u11A:
undetectable		 2b7zA-1u11A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 GLY A  85
ALA A  84
ASP A  33
GLY A 136
ILE A 135
 CIT  A1001 (-4.3A)
CIT  A1001 (-3.8A)
CIT  A1001 (-2.9A)
None
None
 1.04A 2b7zB-1u11A:
undetectable		 2b7zB-1u11A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 7 VAL A 130
ILE A 121
ALA A  82
GLY A 131
THR A 132
 None
 1.38A 2xrzB-1u11A:
undetectable		 2xrzB-1u11A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 LEU A 103
ALA A  40
LEU A  47
VAL A  79
ILE A  81
 None
 0.90A 3em6B-1u11A:
undetectable		 3em6B-1u11A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 ILE A  55
GLY A  29
ALA A  82
ASP A  33
ALA A  58
 None
CIT  A1001 (-3.1A)
None
CIT  A1001 (-2.9A)
None
 1.00A 3jb1A-1u11A:
undetectable		 3jb1A-1u11A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 9 GLY A  85
ALA A  84
ASP A  33
GLY A 136
ILE A 135
 CIT  A1001 (-4.3A)
CIT  A1001 (-3.8A)
CIT  A1001 (-2.9A)
None
None
 0.95A 3ogpA-1u11A:
undetectable		 3ogpA-1u11A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 8 GLY A  85
ALA A  84
ASP A  33
GLY A 136
ILE A 135
 CIT  A1001 (-4.3A)
CIT  A1001 (-3.8A)
CIT  A1001 (-2.9A)
None
None
 1.16A 3so9A-1u11A:
undetectable		 3so9A-1u11A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 LEU A  44
VAL A  24
ALA A 144
LEU A 162
LEU A 158
 None
 1.09A 4i1rA-1u11A:
4.4		 4i1rA-1u11A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 ALA A 140
GLY A 139
ILE A  81
GLY A  83
ARG A  38
 None
 1.31A 4obwD-1u11A:
undetectable		 4obwD-1u11A:
18.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		3 / 3 ASN A 155
ALA A 157
ARG A 161
 None
 0.15A 5cvtB-1u11A:
31.7		 5cvtB-1u11A:
98.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)
(Acetobacter
aceti) 		5 / 12 LEU A 103
ALA A  40
ASP A  41
VAL A  79
ILE A  81
 None
 1.23A 6difA-1u11A:
undetectable		 6difA-1u11A:
18.68