SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LCV_B_SAMB301_0 (SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM)	1u1z	(3R)-HYDROXYMYRISTOY L-[ACYL CARRIER PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	5 / 12	PHE A 45 ALA A 64 ILE A 61 LEU A 109 LEU A 18	None	1.13A	3lcvB-1u1zA: undetectable	3lcvB-1u1zA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KIC_B_SAMB401_0 (METHYLTRANSFERASE MPPJ)	1u1z	(3R)-HYDROXYMYRISTOY L-[ACYL CARRIER PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	5 / 12	ILE A 139 CYH A 141 GLY A 73 ILE A 33 ALA A 111	None	1.12A	4kicB-1u1zA: undetectable	4kicB-1u1zA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN)	1u1z	(3R)-HYDROXYMYRISTOY L-[ACYL CARRIER PROTEIN] DEHYDRATASE (Pseudomonas aeruginosa)	5 / 12	LEU A 95 LEU A 107 ALA A 127 VAL A 134 GLY A 58	None	0.98A	4rn6B-1u1zA: undetectable	4rn6B-1u1zA: 17.18