SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u2c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 1u2c DYSTROGLYCAN
(Mus
musculus) 		5 / 12 LEU A 255
ALA A 254
MET A 284
GLY A 289
LEU A 208
 None
 1.19A 5gs4A-1u2cA:
undetectable		 5gs4A-1u2cA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 1u2c DYSTROGLYCAN
(Mus
musculus) 		4 / 5 GLU A 157
VAL A 226
LEU A 255
HIS A 296
 None
 1.02A 6dyoA-1u2cA:
undetectable		 6dyoA-1u2cA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 1u2c DYSTROGLYCAN
(Mus
musculus) 		3 / 3 LEU A 220
GLN A 213
LYS A 203
 None
 0.82A 6exiB-1u2cA:
undetectable		 6exiB-1u2cA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 1u2c DYSTROGLYCAN
(Mus
musculus) 		3 / 3 LEU A 220
GLN A 213
LYS A 203
 None
 0.86A 6exiA-1u2cA:
undetectable		 6exiA-1u2cA:
17.03