SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.01A	1dfoA-1u2zA: undetectable	1dfoA-1u2zA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.01A	1dfoB-1u2zA: undetectable	1dfoB-1u2zA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.01A	1dfoC-1u2zA: undetectable	1dfoC-1u2zA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.00A	1dfoD-1u2zA: undetectable	1dfoD-1u2zA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 SER A 428 ALA A 427 SER A 368 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.14A	1eqbA-1u2zA: undetectable	1eqbA-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.02A	1eqbA-1u2zA: undetectable	1eqbA-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 SER A 428 ALA A 427 SER A 368 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.14A	1eqbB-1u2zA: undetectable	1eqbB-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.02A	1eqbB-1u2zA: undetectable	1eqbB-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 SER A 428 ALA A 427 SER A 368 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.14A	1eqbC-1u2zA: 2.4	1eqbC-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.02A	1eqbC-1u2zA: 2.4	1eqbC-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 SER A 428 ALA A 427 SER A 368 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.14A	1eqbD-1u2zA: undetectable	1eqbD-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 401 VAL A 461 SER A 428 ALA A 427 PHE A 367	SAH A 801 ( 4.2A) None None None None	1.01A	1eqbD-1u2zA: undetectable	1eqbD-1u2zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	LEU A 376 VAL A 541 SER A 542 VAL A 383 LEU A 477	None	1.24A	1ie9A-1u2zA: undetectable	1ie9A-1u2zA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	TYR A 372 LEU A 376 VAL A 541 SER A 542 VAL A 383	None	1.39A	1ie9A-1u2zA: undetectable	1ie9A-1u2zA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW3_A_SAMA500_0 (HISTONE METHYLTRANSFERASE DOT1L)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	7 / 12	TYR A 372 GLU A 374 ASP A 397 GLY A 399 PHE A 460 ASN A 479 PHE A 483	None None SAH A 801 (-3.0A) SAH A 801 (-3.1A) SAH A 801 (-3.5A) SAH A 801 (-4.4A) SAH A 801 ( 4.7A)	0.44A	1nw3A-1u2zA: 29.1	1nw3A-1u2zA: 23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q6I_A_FK5A301_1 (FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 9	TYR A 445 LEU A 444 ILE A 319 TYR A 315 ILE A 272	None	1.14A	1q6iA-1u2zA: undetectable	1q6iA-1u2zA: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RK3_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	TYR A 372 LEU A 376 VAL A 541 SER A 542 VAL A 383	None	1.45A	1rk3A-1u2zA: undetectable	1rk3A-1u2zA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S1U_A_NVPA999_1 (REVERSE TRANSCRIPTASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 10	ILE A 476 LYS A 499 VAL A 555 GLY A 501 LEU A 495	None	1.40A	1s1uA-1u2zA: undetectable	1s1uA-1u2zA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	6 / 12	ASP A 397 GLY A 399 GLY A 401 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.0A) SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	0.55A	2nxeA-1u2zA: 8.7	2nxeA-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	6 / 12	ASP A 397 GLY A 399 LEU A 477 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.0A) SAH A 801 (-3.1A) None SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	1.12A	2nxeA-1u2zA: 8.7	2nxeA-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	ASP A 397 LEU A 398 GLY A 399 GLY A 401 ASN A 479	SAH A 801 (-3.0A) None SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-4.4A)	0.65A	2nxeA-1u2zA: 8.7	2nxeA-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	6 / 12	ASP A 397 GLY A 399 GLY A 401 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.0A) SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	0.63A	2nxeB-1u2zA: 9.3	2nxeB-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	6 / 12	ASP A 397 GLY A 399 LEU A 477 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.0A) SAH A 801 (-3.1A) None SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	1.16A	2nxeB-1u2zA: 9.3	2nxeB-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	ASP A 397 LEU A 398 GLY A 399 GLY A 401 ASN A 479	SAH A 801 (-3.0A) None SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-4.4A)	0.63A	2nxeB-1u2zA: 9.3	2nxeB-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA507_0 (CHORISMATE SYNTHASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	3 / 3	LEU A 529 ASN A 527 ARG A 511	None	0.93A	2qhfA-1u2zA: undetectable	2qhfA-1u2zA: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 399 GLY A 401 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	0.60A	2zbpA-1u2zA: 9.2	2zbpA-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 399 LEU A 477 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.1A) None SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	1.03A	2zbpA-1u2zA: 9.2	2zbpA-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZLC_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	TYR A 372 LEU A 376 VAL A 541 SER A 542 VAL A 383	None	1.41A	2zlcA-1u2zA: undetectable	2zlcA-1u2zA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZSE_A_PAUA600_0 (PANTOTHENATE KINASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	4 / 7	PHE A 308 PHE A 255 ILE A 312 ASN A 313	None	1.17A	2zseA-1u2zA: undetectable	2zseA-1u2zA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZTH_A_SAMA305_1 (CATECHOL O-METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	3 / 3	SER A 340 GLU A 273 ASP A 181	None	0.82A	2zthA-1u2zA: 9.8	2zthA-1u2zA: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_G_SAMG302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 399 GLY A 401 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	0.73A	3cjtG-1u2zA: 9.2	3cjtG-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 399 GLY A 401 ILE A 423 ASN A 479 LEU A 487	SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-4.4A) SAH A 801 ( 4.9A)	0.71A	3cjtO-1u2zA: 9.1	3cjtO-1u2zA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS8_A_BRLA503_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	CYH A 442 ILE A 342 LEU A 346 LEU A 193 TYR A 191	None	1.09A	3cs8A-1u2zA: 0.0	3cs8A-1u2zA: 24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MED_A_65BA561_0 (P51 REVERSE TRANSCRIPTASE P66 REVERSE TRANSCRIPTASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	ASN A 404 VAL A 407 VAL A 402 TYR A 435 GLY A 403	SAH A 801 ( 4.9A) None None None None	1.23A	3medA-1u2zA: undetectable 3medB-1u2zA: undetectable	3medA-1u2zA: 21.93 3medB-1u2zA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_0 (HISTONE-LYSINE N-METHYLTRANSFERASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	7 / 12	TYR A 372 GLY A 373 GLU A 374 GLY A 399 PHE A 460 ASN A 479 PHE A 483	None SAH A 801 (-4.2A) None SAH A 801 (-3.1A) SAH A 801 (-3.5A) SAH A 801 (-4.4A) SAH A 801 ( 4.7A)	0.46A	3qowA-1u2zA: 18.1	3qowA-1u2zA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT3_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	TYR A 372 LEU A 376 VAL A 541 SER A 542 VAL A 383	None	1.40A	3vt3A-1u2zA: undetectable	3vt3A-1u2zA: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT7_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	TYR A 372 LEU A 376 VAL A 541 SER A 542 VAL A 383	None	1.41A	3vt7A-1u2zA: undetectable	3vt7A-1u2zA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A79_A_P1BA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	PRO A 356 ILE A 210 PHE A 345 TYR A 445 TYR A 205	None	1.27A	4a79A-1u2zA: 0.7	4a79A-1u2zA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A79_B_P1BB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	PRO A 356 ILE A 210 PHE A 345 TYR A 445 TYR A 205	None	1.26A	4a79B-1u2zA: undetectable	4a79B-1u2zA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_A_SAMA602_1 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	3 / 3	ASP A 397 ASN A 404 SER A 455	SAH A 801 (-3.0A) SAH A 801 ( 4.9A) None	0.77A	4obwA-1u2zA: 9.3	4obwA-1u2zA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTW_A_DB8A1101_2 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	3 / 3	LEU A 239 LEU A 215 ASN A 263	None	0.45A	4otwA-1u2zA: undetectable	4otwA-1u2zA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4S0V_A_SUVA2001_1 (HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	VAL A 531 GLN A 496 GLU A 492 ILE A 517 ASN A 521	None	1.20A	4s0vA-1u2zA: 2.7	4s0vA-1u2zA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_D_ACTD403_0 (PROTON-GATED ION CHANNEL)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	4 / 4	ILE A 268 ARG A 441 TYR A 251 GLU A 249	None	1.35A	4zzbD-1u2zA: undetectable	4zzbD-1u2zA: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FA8_A_SAMA301_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 399 GLY A 401 ILE A 423 PHE A 460 LEU A 482	SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-3.5A) None	0.76A	5fa8A-1u2zA: 13.5	5fa8A-1u2zA: 16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_A_ADNA401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	4 / 7	GLY A 399 GLU A 422 PHE A 460 ASN A 479	SAH A 801 (-3.1A) SAH A 801 (-2.5A) SAH A 801 (-3.5A) SAH A 801 (-4.4A)	0.24A	5mvsA-1u2zA: 26.1	5mvsA-1u2zA: 25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_B_ADNB401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 8	GLY A 399 GLU A 422 PHE A 460 ASN A 479 PHE A 483	SAH A 801 (-3.1A) SAH A 801 (-2.5A) SAH A 801 (-3.5A) SAH A 801 (-4.4A) SAH A 801 ( 4.7A)	0.28A	5mvsB-1u2zA: 26.1	5mvsB-1u2zA: 25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WY0_A_SAMA800_0 (SMALL RNA 2'-O-METHYLTRANSFERA SE)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 399 GLY A 401 ILE A 423 SER A 459 LEU A 487	SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.7A) SAH A 801 (-3.2A) SAH A 801 ( 4.9A)	0.52A	5wy0A-1u2zA: 8.0	5wy0A-1u2zA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AWT_D_BEZD202_0 (PR 10 PROTEIN)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	3 / 3	PHE A 483 ASP A 486 LYS A 490	SAH A 801 ( 4.7A) None None	0.79A	6awtD-1u2zA: undetectable	6awtD-1u2zA: 17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_A_EY4A501_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	4 / 5	GLN A 408 VAL A 407 PRO A 377 THR A 431	None	1.50A	6cduA-1u2zA: 0.0 6cduB-1u2zA: 0.0	6cduA-1u2zA: 20.83 6cduB-1u2zA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D9K_F_ACTF802_0 (UNCHARACTERIZED PROTEIN)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	3 / 3	TYR A 435 ALA A 410 LEU A 449	None	0.68A	6d9kF-1u2zA: undetectable	6d9kF-1u2zA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NJ9_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 12	GLY A 373 ASP A 397 GLY A 399 GLY A 401 PHE A 460	SAH A 801 (-4.2A) SAH A 801 (-3.0A) SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-3.5A)	0.57A	6nj9K-1u2zA: 3.1	6nj9K-1u2zA: 23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NQA_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1u2z	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Saccharomyces cerevisiae)	5 / 10	ASP A 397 GLY A 399 GLY A 401 ASN A 479 PHE A 483	SAH A 801 (-3.0A) SAH A 801 (-3.1A) SAH A 801 ( 4.2A) SAH A 801 (-4.4A) SAH A 801 ( 4.7A)	0.65A	6nqaK-1u2zA: 21.1	6nqaK-1u2zA: 23.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.01A","1dfoA-1u2zA:undetectable","1dfoA-1u2zA:22.20"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.01A","1dfoB-1u2zA:undetectable","1dfoB-1u2zA:22.20"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.01A","1dfoC-1u2zA:undetectable","1dfoC-1u2zA:22.20"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.00A","1dfoD-1u2zA:undetectable","1dfoD-1u2zA:22.20"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;SER A 428;ALA A 427;SER A 368;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.14A","1eqbA-1u2zA:undetectable","1eqbA-1u2zA:22.40"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.02A","1eqbA-1u2zA:undetectable","1eqbA-1u2zA:22.40"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;SER A 428;ALA A 427;SER A 368;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.14A","1eqbB-1u2zA:undetectable","1eqbB-1u2zA:22.40"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.02A","1eqbB-1u2zA:undetectable","1eqbB-1u2zA:22.40"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;SER A 428;ALA A 427;SER A 368;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.14A","1eqbC-1u2zA:2.4","1eqbC-1u2zA:22.40"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.02A","1eqbC-1u2zA:2.4","1eqbC-1u2zA:22.40"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;SER A 428;ALA A 427;SER A 368;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.14A","1eqbD-1u2zA:undetectable","1eqbD-1u2zA:22.40"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 401;VAL A 461;SER A 428;ALA A 427;PHE A 367","SAH A 801 ( 4.2A);None;None;None;None","1.01A","1eqbD-1u2zA:undetectable","1eqbD-1u2zA:22.40"],["1IE9_A_VDXA500_1","VITAMIN D3 RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"LEU A 376;VAL A 541;SER A 542;VAL A 383;LEU A 477","None","1.24A","1ie9A-1u2zA:undetectable","1ie9A-1u2zA:22.52"],["1IE9_A_VDXA500_1","VITAMIN D3 RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"TYR A 372;LEU A 376;VAL A 541;SER A 542;VAL A 383","None","1.39A","1ie9A-1u2zA:undetectable","1ie9A-1u2zA:22.52"],["1NW3_A_SAMA500_0","HISTONE METHYLTRANSFERASE DOT1L","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",7,"TYR A 372;GLU A 374;ASP A 397;GLY A 399;PHE A 460;ASN A 479;PHE A 483","None;None;SAH A 801 (-3.0A);SAH A 801 (-3.1A);SAH A 801 (-3.5A);SAH A 801 (-4.4A);SAH A 801 ( 4.7A)","0.44A","1nw3A-1u2zA:29.1","1nw3A-1u2zA:23.84"],["1Q6I_A_FK5A301_1","FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"TYR A 445;LEU A 444;ILE A 319;TYR A 315;ILE A 272","None","1.14A","1q6iA-1u2zA:undetectable","1q6iA-1u2zA:19.91"],["1RK3_A_VDXA500_1","VITAMIN D3 RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"TYR A 372;LEU A 376;VAL A 541;SER A 542;VAL A 383","None","1.45A","1rk3A-1u2zA:undetectable","1rk3A-1u2zA:22.70"],["1S1U_A_NVPA999_1","REVERSE TRANSCRIPTASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"ILE A 476;LYS A 499;VAL A 555;GLY A 501;LEU A 495","None","1.40A","1s1uA-1u2zA:undetectable","1s1uA-1u2zA:21.53"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",6,"ASP A 397;GLY A 399;GLY A 401;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.0A);SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","0.55A","2nxeA-1u2zA:8.7","2nxeA-1u2zA:20.81"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",6,"ASP A 397;GLY A 399;LEU A 477;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.0A);SAH A 801 (-3.1A);None;SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","1.12A","2nxeA-1u2zA:8.7","2nxeA-1u2zA:20.81"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"ASP A 397;LEU A 398;GLY A 399;GLY A 401;ASN A 479","SAH A 801 (-3.0A);None;SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-4.4A)","0.65A","2nxeA-1u2zA:8.7","2nxeA-1u2zA:20.81"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",6,"ASP A 397;GLY A 399;GLY A 401;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.0A);SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","0.63A","2nxeB-1u2zA:9.3","2nxeB-1u2zA:20.81"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",6,"ASP A 397;GLY A 399;LEU A 477;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.0A);SAH A 801 (-3.1A);None;SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","1.16A","2nxeB-1u2zA:9.3","2nxeB-1u2zA:20.81"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"ASP A 397;LEU A 398;GLY A 399;GLY A 401;ASN A 479","SAH A 801 (-3.0A);None;SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-4.4A)","0.63A","2nxeB-1u2zA:9.3","2nxeB-1u2zA:20.81"],["2QHF_A_ACTA507_0","CHORISMATE SYNTHASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",3,"LEU A 529;ASN A 527;ARG A 511","None","0.93A","2qhfA-1u2zA:undetectable","2qhfA-1u2zA:21.28"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;GLY A 401;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","0.60A","2zbpA-1u2zA:9.2","2zbpA-1u2zA:20.81"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;LEU A 477;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.1A);None;SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","1.03A","2zbpA-1u2zA:9.2","2zbpA-1u2zA:20.81"],["2ZLC_A_VDXA500_1","VITAMIN D3 RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"TYR A 372;LEU A 376;VAL A 541;SER A 542;VAL A 383","None","1.41A","2zlcA-1u2zA:undetectable","2zlcA-1u2zA:22.51"],["2ZSE_A_PAUA600_0","PANTOTHENATE KINASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",4,"PHE A 308;PHE A 255;ILE A 312;ASN A 313","None","1.17A","2zseA-1u2zA:undetectable","2zseA-1u2zA:21.82"],["2ZTH_A_SAMA305_1","CATECHOL O-METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",3,"SER A 340;GLU A 273;ASP A 181","None","0.82A","2zthA-1u2zA:9.8","2zthA-1u2zA:18.31"],["3CJT_G_SAMG302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;GLY A 401;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","0.73A","3cjtG-1u2zA:9.2","3cjtG-1u2zA:20.81"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;GLY A 401;ILE A 423;ASN A 479;LEU A 487","SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-4.4A);SAH A 801 ( 4.9A)","0.71A","3cjtO-1u2zA:9.1","3cjtO-1u2zA:20.81"],["3CS8_A_BRLA503_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"CYH A 442;ILE A 342;LEU A 346;LEU A 193;TYR A 191","None","1.09A","3cs8A-1u2zA:0.0","3cs8A-1u2zA:24.11"],["3MED_A_65BA561_0","P51 REVERSE TRANSCRIPTASE;P66 REVERSE TRANSCRIPTASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"ASN A 404;VAL A 407;VAL A 402;TYR A 435;GLY A 403","SAH A 801 ( 4.9A);None;None;None;None","1.23A","3medA-1u2zA:undetectable;3medB-1u2zA:undetectable","3medA-1u2zA:21.93;3medB-1u2zA:21.31"],["3QOW_A_SAMA417_0","HISTONE-LYSINE N-METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",7,"TYR A 372;GLY A 373;GLU A 374;GLY A 399;PHE A 460;ASN A 479;PHE A 483","None;SAH A 801 (-4.2A);None;SAH A 801 (-3.1A);SAH A 801 (-3.5A);SAH A 801 (-4.4A);SAH A 801 ( 4.7A)","0.46A","3qowA-1u2zA:18.1","3qowA-1u2zA:25.00"],["3VT3_A_VDXA500_1","VITAMIN D3 RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"TYR A 372;LEU A 376;VAL A 541;SER A 542;VAL A 383","None","1.40A","3vt3A-1u2zA:undetectable","3vt3A-1u2zA:22.86"],["3VT7_A_VDXA500_1","VITAMIN D3 RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"TYR A 372;LEU A 376;VAL A 541;SER A 542;VAL A 383","None","1.41A","3vt7A-1u2zA:undetectable","3vt7A-1u2zA:22.51"],["4A79_A_P1BA601_1","AMINE OXIDASE [FLAVIN-CONTAINING] B","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"PRO A 356;ILE A 210;PHE A 345;TYR A 445;TYR A 205","None","1.27A","4a79A-1u2zA:0.7","4a79A-1u2zA:20.87"],["4A79_B_P1BB601_1","AMINE OXIDASE [FLAVIN-CONTAINING] B","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"PRO A 356;ILE A 210;PHE A 345;TYR A 445;TYR A 205","None","1.26A","4a79B-1u2zA:undetectable","4a79B-1u2zA:20.87"],["4OBW_A_SAMA602_1","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",3,"ASP A 397;ASN A 404;SER A 455","SAH A 801 (-3.0A);SAH A 801 ( 4.9A);None","0.77A","4obwA-1u2zA:9.3","4obwA-1u2zA:22.51"],["4OTW_A_DB8A1101_2","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",3,"LEU A 239;LEU A 215;ASN A 263","None","0.45A","4otwA-1u2zA:undetectable","4otwA-1u2zA:20.00"],["4S0V_A_SUVA2001_1","HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"VAL A 531;GLN A 496;GLU A 492;ILE A 517;ASN A 521","None","1.20A","4s0vA-1u2zA:2.7","4s0vA-1u2zA:21.79"],["4ZZB_D_ACTD403_0","PROTON-GATED ION CHANNEL","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",4,"ILE A 268;ARG A 441;TYR A 251;GLU A 249","None","1.35A","4zzbD-1u2zA:undetectable","4zzbD-1u2zA:23.13"],["5FA8_A_SAMA301_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;GLY A 401;ILE A 423;PHE A 460;LEU A 482","SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-3.5A);None","0.76A","5fa8A-1u2zA:13.5","5fa8A-1u2zA:16.36"],["5MVS_A_ADNA401_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",4,"GLY A 399;GLU A 422;PHE A 460;ASN A 479","SAH A 801 (-3.1A);SAH A 801 (-2.5A);SAH A 801 (-3.5A);SAH A 801 (-4.4A)","0.24A","5mvsA-1u2zA:26.1","5mvsA-1u2zA:25.46"],["5MVS_B_ADNB401_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;GLU A 422;PHE A 460;ASN A 479;PHE A 483","SAH A 801 (-3.1A);SAH A 801 (-2.5A);SAH A 801 (-3.5A);SAH A 801 (-4.4A);SAH A 801 ( 4.7A)","0.28A","5mvsB-1u2zA:26.1","5mvsB-1u2zA:25.46"],["5WY0_A_SAMA800_0","SMALL RNA 2'-O-METHYLTRANSFERASE","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 399;GLY A 401;ILE A 423;SER A 459;LEU A 487","SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.7A);SAH A 801 (-3.2A);SAH A 801 ( 4.9A)","0.52A","5wy0A-1u2zA:8.0","5wy0A-1u2zA:19.59"],["6AWT_D_BEZD202_0","PR 10 PROTEIN","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",3,"PHE A 483;ASP A 486;LYS A 490","SAH A 801 ( 4.7A);None;None","0.79A","6awtD-1u2zA:undetectable","6awtD-1u2zA:17.28"],["6CDU_A_EY4A501_0","CHIMERIC ALPHA1GABAA RECEPTOR","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",4,"GLN A 408;VAL A 407;PRO A 377;THR A 431","None","1.50A","6cduA-1u2zA:0.0;6cduB-1u2zA:0.0","6cduA-1u2zA:20.83;6cduB-1u2zA:20.83"],["6D9K_F_ACTF802_0","UNCHARACTERIZED PROTEIN","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",3,"TYR A 435;ALA A 410;LEU A 449","None","0.68A","6d9kF-1u2zA:undetectable","6d9kF-1u2zA:20.40"],["6NJ9_K_SAMK500_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"GLY A 373;ASP A 397;GLY A 399;GLY A 401;PHE A 460","SAH A 801 (-4.2A);SAH A 801 (-3.0A);SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-3.5A)","0.57A","6nj9K-1u2zA:3.1","6nj9K-1u2zA:23.64"],["6NQA_K_SAMK500_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1u2z","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","Saccharomyces cerevisiae",5,"ASP A 397;GLY A 399;GLY A 401;ASN A 479;PHE A 483","SAH A 801 (-3.0A);SAH A 801 (-3.1A);SAH A 801 ( 4.2A);SAH A 801 (-4.4A);SAH A 801 ( 4.7A)","0.65A","6nqaK-1u2zA:21.1","6nqaK-1u2zA:23.64"]]