SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1u39 AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1
(Homo
sapiens) 		5 / 12 ILE A 104
PHE A  97
ILE A  86
ARG A  88
LEU A 144
 None
 1.11A 1jolA-1u39A:
undetectable		 1jolA-1u39A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1u39 AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1
(Homo
sapiens) 		5 / 12 ILE A 104
PHE A  97
ILE A 151
ARG A  88
LEU A 144
 None
 1.20A 1jolA-1u39A:
undetectable		 1jolA-1u39A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 1u39 AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1
(Homo
sapiens) 		4 / 7 LEU A  85
ILE A 125
ILE A 124
VAL A 132
 None
 0.68A 4ojbA-1u39A:
undetectable		 4ojbA-1u39A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1u39 AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1
(Homo
sapiens) 		5 / 12 ILE A 104
PHE A  97
ILE A 151
ARG A  88
LEU A 144
 None
 1.15A 4qleA-1u39A:
undetectable		 4qleA-1u39A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1u39 AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1
(Homo
sapiens) 		5 / 12 ILE A 104
PHE A  97
ILE A 151
ARG A  88
LEU A 144
 None
 1.17A 4qlgA-1u39A:
undetectable		 4qlgA-1u39A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 1u39 AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1
(Homo
sapiens) 		4 / 4 GLN A 130
VAL A 132
GLU A 126
ILE A 125
 None
 1.37A 5jncA-1u39A:
0.0		 5jncA-1u39A:
16.74