SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 233
SER A 236
ASN A 288
 None
 0.59A 1bx4A-1u3dA:
2.9		 1bx4A-1u3dA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.81A 1mt1A-1u3dA:
undetectable
1mt1F-1u3dA:
undetectable		 1mt1A-1u3dA:
7.71
1mt1F-1u3dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ILE A  82
LEU A  67
ASP A  71
LEU A  74
 None
 0.81A 1mt1B-1u3dA:
undetectable
1mt1C-1u3dA:
undetectable		 1mt1B-1u3dA:
12.57
1mt1C-1u3dA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.82A 1mt1G-1u3dA:
undetectable
1mt1J-1u3dA:
undetectable		 1mt1G-1u3dA:
7.71
1mt1J-1u3dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 7 ILE A  82
LEU A  67
ASP A  71
LEU A  74
 None
 0.81A 1mt1H-1u3dA:
undetectable
1mt1K-1u3dA:
undetectable		 1mt1H-1u3dA:
12.57
1mt1K-1u3dA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 8 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.81A 1n13A-1u3dA:
undetectable
1n13F-1u3dA:
undetectable		 1n13A-1u3dA:
7.71
1n13F-1u3dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 7 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.82A 1n13I-1u3dA:
undetectable
1n13L-1u3dA:
undetectable		 1n13I-1u3dA:
7.71
1n13L-1u3dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 LEU A 315
LEU A 407
SER A 410
THR A 404
 None
 1.22A 1tyrA-1u3dA:
undetectable		 1tyrA-1u3dA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 ARG A  20
VAL A 261
GLY A 295
 None
 0.66A 2avvE-1u3dA:
undetectable		 2avvE-1u3dA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLU A 298
ARG A 297
GLU A 173
GLU A 143
TYR A 111
 None
 0.92A 2f0zA-1u3dA:
undetectable		 2f0zA-1u3dA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 110
ASN A 108
ARG A  19
 None
 0.94A 2qhfA-1u3dA:
undetectable		 2qhfA-1u3dA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 7 ILE A  82
LEU A  67
ASP A  71
LEU A  74
 None
 0.83A 2qqcB-1u3dA:
undetectable
2qqcC-1u3dA:
undetectable		 2qqcB-1u3dA:
12.32
2qqcC-1u3dA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 7 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.84A 2qqcA-1u3dA:
undetectable
2qqcF-1u3dA:
undetectable		 2qqcA-1u3dA:
8.57
2qqcF-1u3dA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 7 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.85A 2qqcI-1u3dA:
undetectable
2qqcL-1u3dA:
undetectable		 2qqcI-1u3dA:
8.57
2qqcL-1u3dA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 7 LEU A  67
ASP A  71
LEU A  74
ILE A  82
 None
 0.87A 2qqdA-1u3dA:
undetectable
2qqdE-1u3dA:
undetectable		 2qqdA-1u3dA:
8.79
2qqdE-1u3dA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 ARG A 313
ARG A 378
PRO A 314
 None
 1.09A 2wljA-1u3dA:
undetectable		 2wljA-1u3dA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 5 LYS A 382
ARG A 378
TYR A  53
GLU A 312
 None
 1.48A 2x8oA-1u3dA:
0.0		 2x8oA-1u3dA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 HIS A 255
GLU A 258
HIS A 253
 None
None
NDS  A 512 (-4.3A)
 0.75A 3ba0A-1u3dA:
undetectable		 3ba0A-1u3dA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A  77
GLY A  78
ALA A  41
LEU A  70
ASP A  71
 None
 0.89A 3gwvA-1u3dA:
undetectable		 3gwvA-1u3dA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASP A 139
LEU A 114
SER A 115
LEU A 393
ASP A 392
 None
 1.21A 3ko0G-1u3dA:
0.3
3ko0H-1u3dA:
undetectable
3ko0I-1u3dA:
0.4
3ko0J-1u3dA:
0.4		 3ko0G-1u3dA:
11.39
3ko0H-1u3dA:
11.39
3ko0I-1u3dA:
11.39
3ko0J-1u3dA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 9 LEU A 233
VAL A 287
SER A 286
ILE A 228
ALA A 274
 None
 1.29A 3mdtA-1u3dA:
undetectable		 3mdtA-1u3dA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 TYR A 309
GLU A 394
TYR A 111
 None
 1.02A 3ug8A-1u3dA:
undetectable		 3ug8A-1u3dA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 5 ILE A 361
VAL A 433
LEU A 440
ASP A 345
 None
 1.16A 3wzdA-1u3dA:
undetectable		 3wzdA-1u3dA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 11 PHE A  18
ALA A  29
ASP A 139
GLY A 257
ASN A  27
 None
 1.00A 4dcmA-1u3dA:
undetectable		 4dcmA-1u3dA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		3 / 3 ASP A 119
TRP A 385
SER A  89
 None
 1.06A 4lrhA-1u3dA:
undetectable		 4lrhA-1u3dA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A  20
ARG A 118
ASP A 112
ASP A 119
 None
 1.07A 4xqeA-1u3dA:
2.3		 4xqeA-1u3dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A 118
ARG A  20
ASP A 119
ASP A 112
 None
 0.94A 4xqeA-1u3dA:
2.3		 4xqeA-1u3dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A  20
ARG A 118
ASP A 112
ASP A 119
 None
 1.05A 4xqeB-1u3dA:
undetectable		 4xqeB-1u3dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A 118
ARG A  20
ASP A 119
ASP A 112
 None
 0.93A 4xqeB-1u3dA:
undetectable		 4xqeB-1u3dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 8 ARG A  20
ARG A 118
ASP A 112
ASP A 119
 None
 1.06A 4xqgA-1u3dA:
2.3		 4xqgA-1u3dA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 8 ARG A 118
ARG A  20
ASP A 119
ASP A 112
 None
 0.93A 4xqgA-1u3dA:
2.3		 4xqgA-1u3dA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 8 ARG A  20
ARG A 118
ASP A 112
ASP A 119
 None
 1.05A 4xqgB-1u3dA:
undetectable		 4xqgB-1u3dA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 8 ARG A 118
ARG A  20
ASP A 119
ASP A 112
 None
 0.94A 4xqgB-1u3dA:
undetectable		 4xqgB-1u3dA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 9 ALA A 333
GLN A 336
GLU A 328
LEU A 373
ILE A 474
 None
 1.46A 5i73A-1u3dA:
0.1		 5i73A-1u3dA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		5 / 11 ASN A 137
VAL A 259
SER A 260
ASP A  26
LEU A 250
 None
 1.45A 5jh7B-1u3dA:
undetectable		 5jh7B-1u3dA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ASP A 139
GLU A 394
ASP A 112
GLU A  50
 None
 1.35A 6mn5C-1u3dA:
undetectable		 6mn5C-1u3dA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1u3d CRYPTOCHROME 1
APOPROTEIN
(Arabidopsis
thaliana) 		4 / 6 ASP A 139
GLU A 394
ASP A 112
GLU A  50
 None
 1.45A 6mn5D-1u3dA:
undetectable		 6mn5D-1u3dA:
9.88