SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_A_ACTA1872_0 (FPRA)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	4 / 5	SER A 100 ASN A 99 ALA A 28 ASP A 30	None	1.27A	1lqtA-1u3hA: undetectable 1lqtB-1u3hA: undetectable	1lqtA-1u3hA: 13.17 1lqtB-1u3hA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_A_ACTA1429_0 (FPRA)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	4 / 5	SER A 100 ASN A 99 ALA A 28 ASP A 30	None	1.25A	1lquA-1u3hA: undetectable 1lquB-1u3hA: undetectable	1lquA-1u3hA: 13.17 1lquB-1u3hA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QU2_A_MRCA1993_2 (ISOLEUCYL-TRNA SYNTHETASE)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	3 / 3	GLU A 16 TRP A 13 LYS A 72	None	1.43A	1qu2A-1u3hA: undetectable	1qu2A-1u3hA: 7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_B_ANWB99_0 (PROTEIN S100-A13)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	4 / 8	ALA A 78 THR A 63 PHE A 62 ASP A 84	None	1.17A	2kotB-1u3hA: undetectable	2kotB-1u3hA: 24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FRQ_A_ERYA195_0 (REPRESSOR PROTEIN MPHR(A))	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	5 / 12	THR A 102 VAL A 3 TYR A 24 LEU A 73 ILE A 64	None	1.28A	3frqA-1u3hA: undetectable	3frqA-1u3hA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS6_B_EPAB1_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	5 / 12	PHE A 66 ILE A 49 PHE A 32 TYR A 24 ALA A 98	None	0.94A	3hs6B-1u3hA: undetectable	3hs6B-1u3hA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_A_LNLA701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	5 / 12	PHE A 66 ILE A 49 PHE A 32 TYR A 24 ALA A 98	None	0.99A	4e1gA-1u3hA: undetectable	4e1gA-1u3hA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_B_LNLB701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1u3h	T-CELL RECEPTOR ALPHA-CHAIN (Mus musculus)	5 / 12	PHE A 66 ILE A 49 PHE A 32 TYR A 24 ALA A 98	None	0.98A	4e1gB-1u3hA: undetectable	4e1gB-1u3hA: 10.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_A_ACTA1872_0","FPRA","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",4,"SER A 100;ASN A  99;ALA A  28;ASP A  30","None","1.27A","1lqtA-1u3hA:undetectable;1lqtB-1u3hA:undetectable","1lqtA-1u3hA:13.17;1lqtB-1u3hA:13.17"],["1LQU_A_ACTA1429_0","FPRA","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",4,"SER A 100;ASN A  99;ALA A  28;ASP A  30","None","1.25A","1lquA-1u3hA:undetectable;1lquB-1u3hA:undetectable","1lquA-1u3hA:13.17;1lquB-1u3hA:13.17"],["1QU2_A_MRCA1993_2","ISOLEUCYL-TRNA SYNTHETASE","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",3,"GLU A  16;TRP A  13;LYS A  72","None","1.43A","1qu2A-1u3hA:undetectable","1qu2A-1u3hA:7.76"],["2KOT_B_ANWB99_0","PROTEIN S100-A13","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",4,"ALA A  78;THR A  63;PHE A  62;ASP A  84","None","1.17A","2kotB-1u3hA:undetectable","2kotB-1u3hA:24.79"],["3FRQ_A_ERYA195_0","REPRESSOR PROTEIN MPHR(A)","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",5,"THR A 102;VAL A   3;TYR A  24;LEU A  73;ILE A  64","None","1.28A","3frqA-1u3hA:undetectable","3frqA-1u3hA:20.00"],["3HS6_B_EPAB1_1","PROSTAGLANDIN G\/H SYNTHASE 2","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",5,"PHE A  66;ILE A  49;PHE A  32;TYR A  24;ALA A  98","None","0.94A","3hs6B-1u3hA:undetectable","3hs6B-1u3hA:10.40"],["4E1G_A_LNLA701_1","PROSTAGLANDIN G\/H SYNTHASE 2","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",5,"PHE A  66;ILE A  49;PHE A  32;TYR A  24;ALA A  98","None","0.99A","4e1gA-1u3hA:undetectable","4e1gA-1u3hA:10.40"],["4E1G_B_LNLB701_1","PROSTAGLANDIN G\/H SYNTHASE 2","1u3h","T-CELL RECEPTOR ALPHA-CHAIN","Mus musculus",5,"PHE A  66;ILE A  49;PHE A  32;TYR A  24;ALA A  98","None","0.98A","4e1gB-1u3hA:undetectable","4e1gB-1u3hA:10.40"]]