SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u53'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		4 / 8 TYR A 158
LEU A  22
LEU A 141
GLU A  97
 None
 1.03A 1i7zA-1u53A:
undetectable		 1i7zA-1u53A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 LEU A 141
TYR A 158
GLY A 162
 None
 0.42A 2ocuA-1u53A:
undetectable		 2ocuA-1u53A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		4 / 7 TYR A 153
PHE A  67
ILE A  82
ASN A  61
 None
 1.04A 2zseA-1u53A:
undetectable		 2zseA-1u53A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		4 / 7 GLU A 137
TRP A 135
LEU A 118
ASN A 163
 None
 1.30A 3k8mA-1u53A:
undetectable		 3k8mA-1u53A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.71A 5qglA-1u53A:
undetectable		 5qglA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.66A 5qguA-1u53A:
undetectable		 5qguA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.69A 5qgvA-1u53A:
undetectable		 5qgvA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.67A 5qgwA-1u53A:
undetectable		 5qgwA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.69A 5qgxA-1u53A:
undetectable		 5qgxA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.70A 5qh1A-1u53A:
undetectable		 5qh1A-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.68A 5qh4A-1u53A:
undetectable		 5qh4A-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.66A 5qh9A-1u53A:
undetectable		 5qh9A-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.67A 5qhcA-1u53A:
undetectable		 5qhcA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.67A 5qheA-1u53A:
undetectable		 5qheA-1u53A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1u53 SECRETED PROTEIN
ASP-2
(Necator
americanus) 		3 / 3 VAL A 145
VAL A 154
GLN A  98
 None
 0.68A 5qhfA-1u53A:
undetectable		 5qhfA-1u53A:
22.33