SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u5k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1u5k HYPOTHETICAL PROTEIN
(Deinococcus
radiodurans) 		5 / 10 GLY A  10
VAL A  56
GLY A  57
THR A  29
VAL A  12
 None
 0.93A 1v3qE-1u5kA:
undetectable		 1v3qE-1u5kA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1u5k HYPOTHETICAL PROTEIN
(Deinococcus
radiodurans) 		5 / 11 THR A  29
VAL A  56
GLY A  57
VAL A  60
VAL A  71
 None
 1.03A 2a1nA-1u5kA:
undetectable		 2a1nA-1u5kA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1u5k HYPOTHETICAL PROTEIN
(Deinococcus
radiodurans) 		4 / 7 ARG A   8
ALA A  69
VAL A  58
VAL A  71
 None
 0.88A 3o14A-1u5kA:
undetectable		 3o14A-1u5kA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1u5k HYPOTHETICAL PROTEIN
(Deinococcus
radiodurans) 		5 / 12 VAL A  25
ARG A  15
ILE A  11
LEU A  76
LEU A  52
 None
 1.04A 4m11B-1u5kA:
undetectable		 4m11B-1u5kA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1u5k HYPOTHETICAL PROTEIN
(Deinococcus
radiodurans) 		4 / 8 GLY A 169
THR A 150
VAL A 194
LEU A 141
 None
 0.81A 6czmD-1u5kA:
undetectable
6czmF-1u5kA:
undetectable		 6czmD-1u5kA:
23.08
6czmF-1u5kA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1u5k HYPOTHETICAL PROTEIN
(Deinococcus
radiodurans) 		3 / 3 LEU A  76
GLY A  57
PHE A 113
 None
 0.65A 6exiC-1u5kA:
undetectable		 6exiC-1u5kA:
15.61