SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 ALA A  77
VAL A   8
TRP A  75
 None
 0.91A 1av2A-1u5wA:
undetectable
1av2B-1u5wA:
undetectable		 1av2A-1u5wA:
6.18
1av2B-1u5wA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 ALA A  10
VAL A   8
TRP A  75
 None
 0.78A 1w5uA-1u5wA:
undetectable
1w5uB-1u5wA:
undetectable		 1w5uA-1u5wA:
6.18
1w5uB-1u5wA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 ALA A  77
VAL A   8
TRP A  75
 None
 0.91A 1w5uA-1u5wA:
undetectable
1w5uB-1u5wA:
undetectable		 1w5uA-1u5wA:
6.18
1w5uB-1u5wA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 TRP A  75
ALA A  77
VAL A   8
 None
 0.92A 1w5uA-1u5wA:
undetectable
1w5uB-1u5wA:
undetectable		 1w5uA-1u5wA:
6.18
1w5uB-1u5wA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		4 / 6 THR A  87
LEU A 123
VAL A 126
VAL A 145
 None
 1.05A 2feuA-1u5wA:
undetectable		 2feuA-1u5wA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 TRP A  75
ALA A  77
VAL A   8
 None
 0.81A 2izqC-1u5wA:
undetectable
2izqD-1u5wA:
undetectable		 2izqC-1u5wA:
6.18
2izqD-1u5wA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		4 / 6 THR A  87
LEU A 123
VAL A 126
VAL A 145
 None
 1.08A 2zuiA-1u5wA:
undetectable		 2zuiA-1u5wA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 TRP A  75
ALA A  77
VAL A   8
 None
 1.02A 3l8lA-1u5wA:
undetectable
3l8lB-1u5wA:
undetectable		 3l8lA-1u5wA:
6.18
3l8lB-1u5wA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		3 / 3 TRP A  75
ALA A  77
VAL A   8
 None
 0.80A 3l8lC-1u5wA:
undetectable
3l8lD-1u5wA:
undetectable		 3l8lC-1u5wA:
6.18
3l8lD-1u5wA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		4 / 7 THR A  87
LEU A 123
VAL A 126
VAL A 145
 None
 1.01A 3wrlE-1u5wA:
undetectable		 3wrlE-1u5wA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		4 / 7 THR A  87
LEU A 123
VAL A 126
VAL A 145
 None
 1.04A 3wrmA-1u5wA:
undetectable		 3wrmA-1u5wA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1u5w HYPOTHETICAL UPF0244
PROTEIN YJJX
(Escherichia
coli) 		5 / 8 LYS A 140
ALA A 142
GLY A 124
LEU A 123
LEU A 109
 None
 1.43A 4po0A-1u5wA:
undetectable		 4po0A-1u5wA:
14.58