SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RQP_A_SAMA500_1 (5'-FLUORO-5'-DEOXYAD ENOSINE SYNTHASE)	1u6l	HYPOTHETICAL PROTEIN (Pseudomonas aeruginosa)	4 / 7	ASP A 125 PHE A 127 TRP A 131 PHE A 11	None	1.48A	1rqpB-1u6lA: undetectable	1rqpB-1u6lA: 17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7U_B_SAMB1299_1 (5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE)	1u6l	HYPOTHETICAL PROTEIN (Pseudomonas aeruginosa)	4 / 7	ASP A 125 PHE A 127 TRP A 131 PHE A 11	None	1.46A	2v7uB-1u6lA: undetectable	2v7uB-1u6lA: 17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K8M_A_ACRA720_1 (ALPHA-AMYLASE, SUSG)	1u6l	HYPOTHETICAL PROTEIN (Pseudomonas aeruginosa)	4 / 7	TYR A 22 GLU A 17 LEU A 26 TRP A 131	None	1.40A	3k8mA-1u6lA: undetectable	3k8mA-1u6lA: 12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WQW_A_GCSA502_1 (CHITINASE)	1u6l	HYPOTHETICAL PROTEIN (Pseudomonas aeruginosa)	4 / 5	GLY A 128 TRP A 131 ALA A 130 PHE A 98	None	1.35A	3wqwA-1u6lA: 0.0	3wqwA-1u6lA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAR_A_ERMA2001_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562)	1u6l	HYPOTHETICAL PROTEIN (Pseudomonas aeruginosa)	5 / 12	LEU A 101 ASP A 125 PHE A 11 LEU A 30 PHE A 19	None	1.45A	4iarA-1u6lA: undetectable	4iarA-1u6lA: 15.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RQP_A_SAMA500_1","5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE","1u6l","HYPOTHETICAL PROTEIN","Pseudomonas aeruginosa",4,"ASP A 125;PHE A 127;TRP A 131;PHE A  11","None","1.48A","1rqpB-1u6lA:undetectable","1rqpB-1u6lA:17.33"],["2V7U_B_SAMB1299_1","5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE","1u6l","HYPOTHETICAL PROTEIN","Pseudomonas aeruginosa",4,"ASP A 125;PHE A 127;TRP A 131;PHE A  11","None","1.46A","2v7uB-1u6lA:undetectable","2v7uB-1u6lA:17.33"],["3K8M_A_ACRA720_1","ALPHA-AMYLASE, SUSG","1u6l","HYPOTHETICAL PROTEIN","Pseudomonas aeruginosa",4,"TYR A  22;GLU A  17;LEU A  26;TRP A 131","None","1.40A","3k8mA-1u6lA:undetectable","3k8mA-1u6lA:12.28"],["3WQW_A_GCSA502_1","CHITINASE","1u6l","HYPOTHETICAL PROTEIN","Pseudomonas aeruginosa",4,"GLY A 128;TRP A 131;ALA A 130;PHE A  98","None","1.35A","3wqwA-1u6lA:0.0","3wqwA-1u6lA:19.07"],["4IAR_A_ERMA2001_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562","1u6l","HYPOTHETICAL PROTEIN","Pseudomonas aeruginosa",5,"LEU A 101;ASP A 125;PHE A  11;LEU A  30;PHE A  19","None","1.45A","4iarA-1u6lA:undetectable","4iarA-1u6lA:15.71"]]