SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u78'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1u78 TRANSPOSABLE ELEMENT
TC3 TRANSPOSASE
(Caenorhabditis
elegans) 		5 / 12 ARG A  84
SER A  92
LEU A  61
VAL A  69
ILE A  83
 None
 1.02A 3adxB-1u78A:
undetectable		 3adxB-1u78A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 1u78 TRANSPOSABLE ELEMENT
TC3 TRANSPOSASE
(Caenorhabditis
elegans) 		5 / 10 SER A  48
GLY A  50
LEU A  15
ASP A  16
LYS A  19
 None
 1.07A 3lsfB-1u78A:
undetectable
3lsfE-1u78A:
undetectable		 3lsfB-1u78A:
19.10
3lsfE-1u78A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1u78 TRANSPOSABLE ELEMENT
TC3 TRANSPOSASE
(Caenorhabditis
elegans) 		4 / 8 ARG A  84
SER A  92
LEU A  61
ILE A  83
 None
 0.94A 4xtaB-1u78A:
undetectable		 4xtaB-1u78A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1u78 TRANSPOSABLE ELEMENT
TC3 TRANSPOSASE
(Caenorhabditis
elegans) 		3 / 3 ARG A  36
HIS A  37
ARG A  40
 None
 1.02A 5iaoC-1u78A:
undetectable		 5iaoC-1u78A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1u78 TRANSPOSABLE ELEMENT
TC3 TRANSPOSASE
(Caenorhabditis
elegans) 		3 / 3 ARG A  36
HIS A  37
ARG A  40
 None
 1.04A 5iaoF-1u78A:
undetectable		 5iaoF-1u78A:
28.57