SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		3 / 3 LEU A  58
LEU A 115
PHE A  15
 None
 0.72A 2pgrA-1u7kA:
undetectable		 2pgrA-1u7kA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		3 / 3 TYR A 106
ASP A  54
ASP A  19
 None
 0.86A 3ou6B-1u7kA:
undetectable		 3ou6B-1u7kA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		3 / 3 PRO A  98
ASP A  94
GLU A 100
 None
 0.75A 3v4tC-1u7kA:
undetectable		 3v4tC-1u7kA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		3 / 3 LEU A  72
VAL A  93
ASP A  94
 None
 0.59A 4y8wC-1u7kA:
undetectable		 4y8wC-1u7kA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		4 / 5 LEU A  40
THR A  61
ARG A 119
PRO A  50
 None
 1.30A 6ew0B-1u7kA:
undetectable		 6ew0B-1u7kA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		4 / 5 LEU A  40
THR A  61
ARG A 119
PRO A  50
 None
 1.30A 6ew0D-1u7kA:
0.0		 6ew0D-1u7kA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		4 / 5 LEU A  40
THR A  61
ARG A 119
PRO A  50
 None
 1.30A 6ew0H-1u7kA:
undetectable		 6ew0H-1u7kA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 1u7k GAG POLYPROTEIN
(Murine
leukemia
virus) 		4 / 5 LEU A  40
THR A  61
ARG A 119
PRO A  50
 None
 1.30A 6ew0I-1u7kA:
0.0		 6ew0I-1u7kA:
19.12