SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CEA_A_ACAA90_1 (PLASMINOGEN)	1u7p	MAGNESIUM-DEPENDENT PHOSPHATASE-1 (Mus musculus)	4 / 8	ASP A 13 TRP A 17 ARG A 93 THR A 71	WO4 A 505 ( 3.9A) None None WO4 A 505 (-4.8A)	1.39A	1ceaA-1u7pA: undetectable 1ceaB-1u7pA: undetectable	1ceaA-1u7pA: 15.34 1ceaB-1u7pA: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AB2_B_SNLB503_2 (MINERALOCORTICOID RECEPTOR)	1u7p	MAGNESIUM-DEPENDENT PHOSPHATASE-1 (Mus musculus)	4 / 5	LEU A 16 LEU A 47 LEU A 80 LEU A 81	None	1.02A	2ab2B-1u7pA: 0.0	2ab2B-1u7pA: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1478_0 (TRANSLATION ELONGATION FACTOR SELB)	1u7p	MAGNESIUM-DEPENDENT PHOSPHATASE-1 (Mus musculus)	4 / 6	ASP A 122 THR A 137 THR A 15 PHE A 10	MG A 501 ( 4.4A) None None None	1.01A	4acbC-1u7pA: 2.8	4acbC-1u7pA: 16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CFS_A_TOYA203_1 (AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN)	1u7p	MAGNESIUM-DEPENDENT PHOSPHATASE-1 (Mus musculus)	4 / 8	ASP A 123 ASP A 11 ASP A 122 TYR A 96	MG A 501 (-2.7A) MG A 501 ( 2.6A) MG A 501 ( 4.4A) None	1.07A	5cfsA-1u7pA: undetectable	5cfsA-1u7pA: 23.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CEA_A_ACAA90_1","PLASMINOGEN;PLASMINOGEN","1u7p","MAGNESIUM-DEPENDENT PHOSPHATASE-1","Mus musculus",4,"ASP A  13;TRP A  17;ARG A  93;THR A  71","WO4 A 505 ( 3.9A);None;None;WO4 A 505 (-4.8A)","1.39A","1ceaA-1u7pA:undetectable;1ceaB-1u7pA:undetectable","1ceaA-1u7pA:15.34;1ceaB-1u7pA:15.34"],["2AB2_B_SNLB503_2","MINERALOCORTICOID RECEPTOR","1u7p","MAGNESIUM-DEPENDENT PHOSPHATASE-1","Mus musculus",4,"LEU A  16;LEU A  47;LEU A  80;LEU A  81","None","1.02A","2ab2B-1u7pA:0.0","2ab2B-1u7pA:21.61"],["4ACB_C_DXCC1478_0","TRANSLATION ELONGATION FACTOR SELB","1u7p","MAGNESIUM-DEPENDENT PHOSPHATASE-1","Mus musculus",4,"ASP A 122;THR A 137;THR A  15;PHE A  10"," MG A 501 ( 4.4A);None;None;None","1.01A","4acbC-1u7pA:2.8","4acbC-1u7pA:16.49"],["5CFS_A_TOYA203_1","AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN","1u7p","MAGNESIUM-DEPENDENT PHOSPHATASE-1","Mus musculus",4,"ASP A 123;ASP A  11;ASP A 122;TYR A  96"," MG A 501 (-2.7A); MG A 501 ( 2.6A); MG A 501 ( 4.4A);None","1.07A","5cfsA-1u7pA:undetectable","5cfsA-1u7pA:23.28"]]