SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 4 ILE A  22
GLN A 214
ILE A 168
LEU A 241
 None
PO4  A1001 ( 4.6A)
None
None
 1.07A 3dzyD-1u83A:
undetectable		 3dzyD-1u83A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 SER A  54
THR A  53
PHE A  81
GLY A  77
ILE A 105
 None
None
None
PO4  A1000 (-3.3A)
None
 1.23A 3fzgA-1u83A:
undetectable		 3fzgA-1u83A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 7 MET A 160
GLU A 161
GLU A 158
TYR A 155
 None
 1.07A 4r87I-1u83A:
undetectable		 4r87I-1u83A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		3 / 3 LEU A 153
VAL A 191
ASP A 192
 None
 0.55A 5x23A-1u83A:
undetectable		 5x23A-1u83A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		5 / 12 ASN A 229
LEU A 133
GLY A  77
ILE A  24
PHE A  81
 GOL  A1110 (-2.9A)
None
PO4  A1000 (-3.3A)
GOL  A1110 (-4.3A)
None
 1.06A 6ectA-1u83A:
undetectable		 6ectA-1u83A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 4 ASP A  45
ILE A 230
PRO A 231
LEU A  23
 None
 1.14A 6mkeB-1u83A:
undetectable		 6mkeB-1u83A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1u83 PHOSPHOSULFOLACTATE
SYNTHASE
(Bacillus
subtilis) 		4 / 4 ASP A  45
ILE A 230
PRO A 231
LEU A  23
 None
 1.12A 6mkeA-1u83A:
undetectable		 6mkeA-1u83A:
15.93