SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  30
TYR A  27
PHE A  59
 None
 0.61A 1eqbB-1u84A:
undetectable		 1eqbB-1u84A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  30
TYR A  27
PHE A  59
 None
 0.60A 1eqbA-1u84A:
undetectable		 1eqbA-1u84A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  30
TYR A  27
PHE A  59
 None
 0.60A 1eqbD-1u84A:
undetectable		 1eqbD-1u84A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  30
TYR A  27
PHE A  59
 None
 0.61A 1eqbC-1u84A:
undetectable		 1eqbC-1u84A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 7 LEU A   9
LEU A  11
TYR A  39
LEU A  75
 None
 0.94A 1kt3A-1u84A:
undetectable		 1kt3A-1u84A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A   9
LEU A  11
ALA A  32
TYR A  39
LEU A  75
 None
 1.33A 1kt5A-1u84A:
undetectable		 1kt5A-1u84A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 11 TYR A  27
ASP A  18
PHE A  59
ILE A  63
PRO A  64
 None
 1.38A 2vcdA-1u84A:
undetectable		 2vcdA-1u84A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1u84 HYPOTHETICAL PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 LEU A  78
LEU A  10
ARG A   8
 None
 0.72A 3hcnB-1u84A:
undetectable		 3hcnB-1u84A:
15.65