SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1u89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 1u89 TALIN 1
(Mus
musculus) 		5 / 12 VAL A 774
ALA A 773
GLU A 810
ILE A 812
THR A 867
 None
 1.30A 3dl9B-1u89A:
undetectable		 3dl9B-1u89A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 1u89 TALIN 1
(Mus
musculus) 		5 / 11 VAL A 808
ILE A 812
SER A 815
LYS A 751
MET A 870
 None
 1.37A 4lhmA-1u89A:
undetectable		 4lhmA-1u89A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 1u89 TALIN 1
(Mus
musculus) 		5 / 11 LEU A 806
ASP A 835
ILE A 862
THR A 809
ILE A 805
 None
 0.98A 4njtA-1u89A:
undetectable		 4njtA-1u89A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 1u89 TALIN 1
(Mus
musculus) 		5 / 11 LEU A 806
ASP A 835
ILE A 862
THR A 809
ILE A 805
 None
 0.92A 4njtC-1u89A:
undetectable		 4njtC-1u89A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1u89 TALIN 1
(Mus
musculus) 		3 / 3 LEU A 764
ASP A 760
ILE A 812
 None
 0.69A 4xi3D-1u89A:
undetectable		 4xi3D-1u89A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 1u89 TALIN 1
(Mus
musculus) 		5 / 12 GLY A 761
ILE A 812
GLY A 817
ALA A 873
ALA A 874
 None
 1.06A 6c2mD-1u89A:
undetectable		 6c2mD-1u89A:
16.43