SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uap'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 1uap PROCOLLAGEN
C-PROTEINASE
ENHANCER PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 141
PRO A 102
VAL A 131
MET A 104
 None
 0.92A 1hrkA-1uapA:
undetectable		 1hrkA-1uapA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 1uap PROCOLLAGEN
C-PROTEINASE
ENHANCER PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 141
PRO A 102
VAL A 131
MET A 104
 None
 0.92A 1hrkB-1uapA:
undetectable		 1hrkB-1uapA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 1uap PROCOLLAGEN
C-PROTEINASE
ENHANCER PROTEIN
(Homo
sapiens) 		4 / 7 LEU A 141
PRO A 102
VAL A 131
MET A 104
 None
 1.01A 2hrcA-1uapA:
undetectable		 2hrcA-1uapA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 1uap PROCOLLAGEN
C-PROTEINASE
ENHANCER PROTEIN
(Homo
sapiens) 		4 / 8 PRO A 125
SER A  48
GLY A 114
SER A  24
 None
 0.97A 3lslA-1uapA:
undetectable
3lslD-1uapA:
undetectable		 3lslA-1uapA:
19.69
3lslD-1uapA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 1uap PROCOLLAGEN
C-PROTEINASE
ENHANCER PROTEIN
(Homo
sapiens) 		4 / 8 SER A  24
PRO A 125
SER A  48
GLY A 114
 None
 0.96A 3lslA-1uapA:
undetectable
3lslD-1uapA:
undetectable		 3lslA-1uapA:
19.69
3lslD-1uapA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 1uap PROCOLLAGEN
C-PROTEINASE
ENHANCER PROTEIN
(Homo
sapiens) 		6 / 12 LEU A  92
GLY A  74
ALA A  75
PRO A 122
THR A  78
VAL A 116
 None
 1.46A 4xdrA-1uapA:
0.0		 4xdrA-1uapA:
18.71