SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.31A	1oe1A-1uatA: 4.3	1oe1A-1uatA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 5	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.31A	1oe2A-1uatA: 8.3	1oe2A-1uatA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.33A	1oe3A-1uatA: 4.3	1oe3A-1uatA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.47A	2fqdA-1uatA: 3.3	2fqdA-1uatA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.45A	2fqeA-1uatA: 3.3	2fqeA-1uatA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.46A	2fqfA-1uatA: 3.4	2fqfA-1uatA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.47A	2fqgA-1uatA: 3.2	2fqgA-1uatA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.33A	2xxgA-1uatA: 8.1	2xxgA-1uatA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 5	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.35A	2xxgC-1uatA: 8.2	2xxgC-1uatA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N65_B_ACTB860_0 (NITRIC OXIDE SYNTHASE)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	3 / 3	GLY A 123 TRP A 48 VAL A 7	None	0.77A	3n65B-1uatA: undetectable	3n65B-1uatA: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	4 / 4	HIS A 46 CYH A 112 HIS A 117 MET A 121	CU A 130 (-3.2A) CU A 130 (-2.1A) CU A 130 (-3.1A) CU A 130 (-3.0A)	0.47A	4ef3A-1uatA: 3.4	4ef3A-1uatA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_B_ACTB804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	1uat	AZURIN ISO-2 (Methylomonas sp. J)	3 / 3	GLY A 123 TRP A 48 VAL A 7	None	0.73A	5vuoB-1uatA: undetectable	5vuoB-1uatA: 15.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.31A","1oe1A-1uatA:4.3","1oe1A-1uatA:16.14"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.31A","1oe2A-1uatA:8.3","1oe2A-1uatA:16.14"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.33A","1oe3A-1uatA:4.3","1oe3A-1uatA:16.14"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.47A","2fqdA-1uatA:3.3","2fqdA-1uatA:12.86"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.45A","2fqeA-1uatA:3.3","2fqeA-1uatA:12.86"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.46A","2fqfA-1uatA:3.4","2fqfA-1uatA:12.86"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.47A","2fqgA-1uatA:3.2","2fqgA-1uatA:12.86"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.33A","2xxgA-1uatA:8.1","2xxgA-1uatA:16.14"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.35A","2xxgC-1uatA:8.2","2xxgC-1uatA:16.14"],["3N65_B_ACTB860_0","NITRIC OXIDE SYNTHASE","1uat","AZURIN ISO-2","Methylomonas sp. J",3,"GLY A 123;TRP A  48;VAL A   7","None","0.77A","3n65B-1uatA:undetectable","3n65B-1uatA:15.82"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","1uat","AZURIN ISO-2","Methylomonas sp. J",4,"HIS A  46;CYH A 112;HIS A 117;MET A 121"," CU A 130 (-3.2A); CU A 130 (-2.1A); CU A 130 (-3.1A); CU A 130 (-3.0A)","0.47A","4ef3A-1uatA:3.4","4ef3A-1uatA:12.86"],["5VUO_B_ACTB804_0","NITRIC OXIDE SYNTHASE, BRAIN","1uat","AZURIN ISO-2","Methylomonas sp. J",3,"GLY A 123;TRP A  48;VAL A   7","None","0.73A","5vuoB-1uatA:undetectable","5vuoB-1uatA:15.82"]]