SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		5 / 10 LEU A  81
ALA A  68
VAL A  86
LEU A  93
GLN A  76
 None
 1.30A 1rlbE-1uc7A:
undetectable		 1rlbE-1uc7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		4 / 7 LEU A  93
PHE A  95
THR A  15
LEU A  80
 None
 1.03A 2eikA-1uc7A:
undetectable
2eikJ-1uc7A:
undetectable		 2eikA-1uc7A:
14.74
2eikJ-1uc7A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		4 / 5 PHE A  46
PHE A  51
PHE A  10
VAL A 107
 None
 1.24A 2lh6A-1uc7A:
undetectable		 2lh6A-1uc7A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		5 / 12 LEU A  66
ALA A  68
LEU A  84
LEU A  80
LEU A  93
 None
 1.14A 3hm1A-1uc7A:
undetectable		 3hm1A-1uc7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		4 / 8 HIS A 119
ASP A 122
ARG A 121
PRO A 125
 None
 1.12A 4uhxA-1uc7A:
undetectable		 4uhxA-1uc7A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		4 / 8 HIS A 119
ASP A 122
ARG A 121
PRO A 125
 None
 1.12A 4uhxA-1uc7A:
undetectable		 4uhxA-1uc7A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		5 / 11 LEU A  66
ALA A  68
LEU A  84
LEU A  80
LEU A  93
 None
 1.22A 4zn7B-1uc7A:
undetectable		 4zn7B-1uc7A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD
(Escherichia
coli) 		4 / 5 LEU A  81
GLY A  88
ASP A  34
ILE A  92
 None
 0.95A 5ik1A-1uc7A:
undetectable		 5ik1A-1uc7A:
14.00