SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ucd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		4 / 4 ALA A 167
GLN A   8
TYR A 112
LEU A 149
 None
 1.10A 1e6wC-1ucdA:
undetectable		 1e6wC-1ucdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		3 / 3 VAL A  72
TRP A  81
TRP A  69
 U5P  A 500 (-3.3A)
None
None
 1.06A 2xdcC-1ucdA:
undetectable
2xdcD-1ucdA:
undetectable		 2xdcC-1ucdA:
11.84
2xdcD-1ucdA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		5 / 12 PHE A   1
PHE A   4
LEU A  36
ALA A 100
PHE A  96
 None
 1.28A 3apxA-1ucdA:
undetectable		 3apxA-1ucdA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		3 / 3 VAL A  72
TRP A  81
TRP A  69
 U5P  A 500 (-3.3A)
None
None
 1.17A 3zq8A-1ucdA:
undetectable
3zq8B-1ucdA:
undetectable		 3zq8A-1ucdA:
11.84
3zq8B-1ucdA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		3 / 3 LYS A  87
HIS A  83
HIS A  88
 U5P  A 500 (-2.7A)
U5P  A 500 (-3.8A)
U5P  A 500 (-3.7A)
 1.42A 5oexA-1ucdA:
0.0		 5oexA-1ucdA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		3 / 3 LYS A  87
HIS A  83
HIS A  88
 U5P  A 500 (-2.7A)
U5P  A 500 (-3.8A)
U5P  A 500 (-3.7A)
 1.42A 5oexB-1ucdA:
0.0		 5oexB-1ucdA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		3 / 3 LYS A  87
HIS A  83
HIS A  88
 U5P  A 500 (-2.7A)
U5P  A 500 (-3.8A)
U5P  A 500 (-3.7A)
 1.43A 5oexC-1ucdA:
undetectable		 5oexC-1ucdA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1ucd RIBONUCLEASE MC
(Momordica
charantia) 		3 / 3 LYS A  87
HIS A  83
HIS A  88
 U5P  A 500 (-2.7A)
U5P  A 500 (-3.8A)
U5P  A 500 (-3.7A)
 1.43A 5oexD-1ucdA:
undetectable		 5oexD-1ucdA:
17.26