SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	1uci	GUANYL-SPECIFIC RIBONUCLEASE SA (Kitasatospora aureofaciens)	5 / 9	TYR A 81 ILE A 92 TYR A 55 THR A 18 ILE A 22	None	1.35A	3p4wA-1uciA: 0.0	3p4wA-1uciA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_B_PFLB410_1 (PROTON-GATED ION CHANNEL)	1uci	GUANYL-SPECIFIC RIBONUCLEASE SA (Kitasatospora aureofaciens)	5 / 9	TYR A 81 ILE A 92 TYR A 55 THR A 18 ILE A 22	None	1.33A	5mvnB-1uciA: 0.0	5mvnB-1uciA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_C_PFLC407_1 (PROTON-GATED ION CHANNEL)	1uci	GUANYL-SPECIFIC RIBONUCLEASE SA (Kitasatospora aureofaciens)	5 / 9	TYR A 81 ILE A 92 TYR A 55 THR A 18 ILE A 22	None	1.33A	5mvnC-1uciA: 0.0	5mvnC-1uciA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_D_PFLD410_1 (PROTON-GATED ION CHANNEL)	1uci	GUANYL-SPECIFIC RIBONUCLEASE SA (Kitasatospora aureofaciens)	5 / 10	TYR A 81 ILE A 92 TYR A 55 THR A 18 ILE A 22	None	1.34A	5mvnD-1uciA: undetectable	5mvnD-1uciA: 21.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3P4W_A_DSFA319_1","GLR4197 PROTEIN","1uci","GUANYL-SPECIFIC RIBONUCLEASE SA","Kitasatospora aureofaciens",5,"TYR A  81;ILE A  92;TYR A  55;THR A  18;ILE A  22","None","1.35A","3p4wA-1uciA:0.0","3p4wA-1uciA:14.67"],["5MVN_B_PFLB410_1","PROTON-GATED ION CHANNEL","1uci","GUANYL-SPECIFIC RIBONUCLEASE SA","Kitasatospora aureofaciens",5,"TYR A  81;ILE A  92;TYR A  55;THR A  18;ILE A  22","None","1.33A","5mvnB-1uciA:0.0","5mvnB-1uciA:21.21"],["5MVN_C_PFLC407_1","PROTON-GATED ION CHANNEL","1uci","GUANYL-SPECIFIC RIBONUCLEASE SA","Kitasatospora aureofaciens",5,"TYR A  81;ILE A  92;TYR A  55;THR A  18;ILE A  22","None","1.33A","5mvnC-1uciA:0.0","5mvnC-1uciA:21.21"],["5MVN_D_PFLD410_1","PROTON-GATED ION CHANNEL","1uci","GUANYL-SPECIFIC RIBONUCLEASE SA","Kitasatospora aureofaciens",5,"TYR A  81;ILE A  92;TYR A  55;THR A  18;ILE A  22","None","1.34A","5mvnD-1uciA:undetectable","5mvnD-1uciA:21.21"]]