SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ucv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1ucv EPHRIN TYPE-A
RECEPTOR 8
(Homo
sapiens) 		4 / 4 LEU A  52
ILE A  50
GLY A  54
ILE A  59
 None
 0.84A 5dzk3-1ucvA:
undetectable
5dzkm-1ucvA:
undetectable		 5dzk3-1ucvA:
14.29
5dzkm-1ucvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ucv EPHRIN TYPE-A
RECEPTOR 8
(Homo
sapiens) 		4 / 5 ILE A  50
GLY A  54
ILE A  59
LEU A  52
 None
 0.80A 5dzkB-1ucvA:
undetectable
5dzkI-1ucvA:
undetectable
5dzkW-1ucvA:
undetectable		 5dzkB-1ucvA:
15.81
5dzkI-1ucvA:
21.74
5dzkW-1ucvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1ucv EPHRIN TYPE-A
RECEPTOR 8
(Homo
sapiens) 		4 / 5 ILE A  50
GLY A  54
ILE A  59
LEU A  52
 None
 0.84A 5dzki-1ucvA:
undetectable
5dzkj-1ucvA:
undetectable
5dzkx-1ucvA:
undetectable		 5dzki-1ucvA:
21.74
5dzkj-1ucvA:
21.74
5dzkx-1ucvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ucv EPHRIN TYPE-A
RECEPTOR 8
(Homo
sapiens) 		4 / 5 ILE A  50
GLY A  54
ILE A  59
LEU A  52
 None
 0.87A 5dzkd-1ucvA:
undetectable
5dzkk-1ucvA:
undetectable
5dzky-1ucvA:
undetectable		 5dzkd-1ucvA:
15.81
5dzkk-1ucvA:
21.74
5dzky-1ucvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1ucv EPHRIN TYPE-A
RECEPTOR 8
(Homo
sapiens) 		4 / 4 ILE A  50
GLY A  54
ILE A  59
LEU A  52
 None
 0.83A 5dzkl-1ucvA:
undetectable
5dzkz-1ucvA:
undetectable		 5dzkl-1ucvA:
21.74
5dzkz-1ucvA:
14.29