SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ud9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 5 LEU A  18
ILE A  47
LEU A  46
SER A  45
 None
 0.91A 2byoA-1ud9A:
1.2		 2byoA-1ud9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  51
PHE A  27
ILE A  87
GLY A 234
 None
 0.89A 2v0mC-1ud9A:
undetectable		 2v0mC-1ud9A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  15
ALA A  25
LEU A  21
LEU A 207
ILE A  14
 None
 1.03A 4dfrB-1ud9A:
undetectable		 4dfrB-1ud9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		3 / 3 LYS A 222
PRO A 223
LYS A 126
 None
 1.33A 4dv7L-1ud9A:
0.3		 4dv7L-1ud9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 6 ASN A 106
ILE A  87
ILE A  88
VAL A   4
 None
 0.96A 4olmA-1ud9A:
undetectable		 4olmA-1ud9A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 7 TYR A   5
PHE A  27
ILE A  34
LEU A 210
 None
 0.91A 4ze3A-1ud9A:
undetectable		 4ze3A-1ud9A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 7 PHE A 176
ILE A 134
GLY A 138
THR A 180
 None
 1.09A 4zxiA-1ud9A:
undetectable		 4zxiA-1ud9A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 8 TYR A   5
PHE A  27
ILE A  34
LEU A 210
 None
 0.90A 5esjA-1ud9A:
undetectable		 5esjA-1ud9A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		4 / 8 TYR A   5
PHE A  27
ILE A  34
LEU A 210
 None
 0.88A 5hs1A-1ud9A:
undetectable		 5hs1A-1ud9A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 1ud9 DNA POLYMERASE
SLIDING CLAMP A
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  36
LEU A  78
PHE A  27
PHE A  67
THR A  71
 None
 1.36A 5ieoA-1ud9A:
undetectable		 5ieoA-1ud9A:
21.22