SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1udx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 10 VAL A 160
VAL A 163
TYR A 241
GLY A 161
LEU A 322
None
1.32A 1fkoA-1udxA:
undetectable
1fkoA-1udxA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 8 ARG A 148
LEU A  58
VAL A  88
VAL A 115
None
0.98A 2bdmA-1udxA:
undetectable
2bdmA-1udxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 11 LEU A 319
ALA A 300
LEU A 299
SER A 272
LEU A 322
None
1.09A 2c12F-1udxA:
undetectable
2c12F-1udxA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 5 ILE A 212
SER A 193
PRO A 194
PRO A 186
None
1.22A 3bjwC-1udxA:
undetectable
3bjwC-1udxA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  15
GLY A 121
GLY A  38
GLY A 142
GLY A  18
None
0.82A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  15
GLY A 142
GLY A 122
GLY A  16
GLY A  18
None
0.86A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  18
GLY A 122
GLY A 142
GLY A  38
GLY A  15
None
0.92A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  35
GLY A 124
GLY A  18
GLY A  36
GLY A  38
None
0.89A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  38
GLY A 121
GLY A  15
GLY A  39
GLY A  41
None
0.89A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  68
GLY A  39
GLY A  38
GLY A  15
GLY A 122
None
0.81A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  68
GLY A  39
GLY A  78
GLY A  16
GLY A  71
None
0.95A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  71
GLY A  38
GLY A  16
GLY A  78
GLY A  68
None
0.93A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 6 GLY A  78
GLY A  68
GLY A  38
GLY A  15
None
0.45A 3bogA-1udxA:
0.1
3bogC-1udxA:
0.0
3bogA-1udxA:
undetectable
3bogC-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
3 / 3 GLY A 145
GLY A  41
GLY A  13
None
0.43A 3bogC-1udxA:
undetectable
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  15
GLY A  41
GLY A  13
GLY A  68
None
0.63A 3bogC-1udxA:
0.0
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  15
GLY A 121
GLY A  38
GLY A 142
None
0.58A 3bogC-1udxA:
0.0
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  18
GLY A  38
GLY A  16
GLY A  71
None
0.66A 3bogC-1udxA:
0.0
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  41
GLY A  68
GLY A  39
GLY A  81
None
0.66A 3bogC-1udxA:
0.0
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  68
GLY A  41
GLY A  13
GLY A  81
None
0.65A 3bogC-1udxA:
0.0
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
3 / 3 GLY A 119
GLY A  39
GLY A  41
None
0.40A 3bogC-1udxA:
undetectable
3bogC-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  15
GLY A  16
GLY A  38
GLY A  68
GLY A  78
None
0.93A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  15
GLY A 121
GLY A  38
GLY A 142
GLY A  18
None
0.77A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  15
GLY A 142
GLY A 122
GLY A  16
GLY A  18
None
0.82A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  18
GLY A 122
GLY A 142
GLY A  38
GLY A  15
None
0.89A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  35
GLY A 124
GLY A  18
GLY A  36
GLY A  38
None
0.84A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  38
GLY A  16
GLY A  68
GLY A 121
GLY A  41
None
0.82A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  38
GLY A  18
GLY A 124
GLY A  71
GLY A  35
None
0.86A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  38
GLY A 121
GLY A  15
GLY A  39
GLY A  41
None
0.83A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  41
GLY A  15
GLY A 121
GLY A  68
GLY A  38
None
0.86A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  68
GLY A  39
GLY A  38
GLY A  15
GLY A 122
None
0.78A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  68
GLY A  39
GLY A  78
GLY A  16
GLY A  71
None
0.91A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  71
GLY A  38
GLY A  16
GLY A  78
GLY A  68
None
0.90A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A  80
GLY A  81
GLY A  42
GLY A  68
GLY A  13
None
0.88A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A 118
GLY A  13
GLY A  15
GLY A  42
GLY A  68
None
0.95A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A 122
GLY A 121
GLY A  15
GLY A  38
GLY A  68
None
0.83A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 6 GLY A 142
GLY A 121
GLY A 119
GLY A  16
GLY A  41
None
0.94A 3bogB-1udxA:
0.0
3bogD-1udxA:
0.1
3bogB-1udxA:
undetectable
3bogD-1udxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  15
GLY A  41
GLY A  13
GLY A  68
None
0.67A 3bogD-1udxA:
0.1
3bogD-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  15
GLY A 121
GLY A  38
GLY A 142
None
0.63A 3bogD-1udxA:
0.1
3bogD-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 4 GLY A  18
GLY A  38
GLY A  16
GLY A  71
None
0.68A 3bogD-1udxA:
0.1
3bogD-1udxA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 12 ALA A 141
GLY A  18
ARG A 363
PHE A 138
TYR A 364
None
1.23A 3bxoA-1udxA:
undetectable
3bxoA-1udxA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 12 ILE A   8
VAL A  85
VAL A 115
PRO A  89
VAL A  94
None
1.03A 3iw1A-1udxA:
undetectable
3iw1A-1udxA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 8 ALA A 104
VAL A  94
LEU A 150
LEU A 114
None
0.79A 3roxA-1udxA:
2.3
3roxA-1udxA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 9 THR A 208
LEU A 162
GLY A 161
THR A 236
VAL A 323
None
1.46A 4c9kA-1udxA:
0.0
4c9kA-1udxA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 9 THR A 208
LEU A 162
GLY A 161
THR A 236
VAL A 323
None
1.46A 4c9kB-1udxA:
undetectable
4c9kB-1udxA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 8 LEU A 315
LEU A 312
GLY A 311
VAL A 279
None
0.78A 4c9nA-1udxA:
undetectable
4c9nA-1udxA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 7 ALA A 275
PRO A 303
LEU A 273
LEU A 240
None
1.07A 4iomA-1udxA:
3.8
4iomA-1udxA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 12 VAL A  20
ALA A  19
GLY A  32
PHE A  22
GLY A  73
None
1.16A 4mm8A-1udxA:
0.0
4mm8A-1udxA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 11 VAL A  20
ALA A  19
GLY A  32
PHE A  22
GLY A  73
None
1.08A 4mm9A-1udxA:
undetectable
4mm9A-1udxA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 12 GLY A  13
ALA A  65
GLY A  41
GLY A  42
GLY A  68
None
0.85A 4o3fA-1udxA:
undetectable
4o3fA-1udxA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 12 GLY A 145
ALA A  12
GLY A 119
GLY A 118
GLY A  15
None
0.88A 4o3fA-1udxA:
undetectable
4o3fA-1udxA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
3 / 3 LEU A 281
LEU A 290
ASN A 277
None
0.73A 4otwA-1udxA:
undetectable
4otwA-1udxA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 8 LEU A 315
VAL A 160
VAL A 199
LEU A 273
None
1.14A 4q0bA-1udxA:
undetectable
4q0bA-1udxA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 6 LEU A 150
LEU A 102
THR A  92
VAL A  88
None
1.06A 4udaA-1udxA:
undetectable
4udaA-1udxA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 11 GLU A 297
LEU A 299
GLU A 254
LEU A 268
ARG A 269
None
0.95A 4wg0K-1udxA:
undetectable
4wg0L-1udxA:
undetectable
4wg0M-1udxA:
undetectable
4wg0K-1udxA:
3.23
4wg0L-1udxA:
3.23
4wg0M-1udxA:
3.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
4 / 5 GLY A  15
ARG A  14
GLY A 145
GLU A 144
None
1.25A 4z2eB-1udxA:
undetectable
4z2eC-1udxA:
4.9
4z2eB-1udxA:
22.92
4z2eC-1udxA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 12 GLY A  13
GLY A 119
GLY A  39
ALA A 116
ASP A  67
None
1.18A 5c0oE-1udxA:
undetectable
5c0oE-1udxA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 7 GLY A  81
GLY A  80
GLY A  39
GLY A 122
GLY A 121
None
0.87A 6ag0A-1udxA:
undetectable
6ag0A-1udxA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus)
5 / 7 GLY A 142
GLY A  16
GLY A  68
GLY A  42
GLY A  13
None
1.08A 6ag0A-1udxA:
undetectable
6ag0A-1udxA:
14.46