SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ueb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1ueb ELONGATION FACTOR P
(Thermus
thermophilus) 		4 / 7 LEU A  44
GLU A  21
LEU A  19
ILE A  63
 None
 0.95A 3s56B-1uebA:
undetectable		 3s56B-1uebA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 1ueb ELONGATION FACTOR P
(Thermus
thermophilus) 		5 / 12 GLY A 156
ALA A 157
PHE A 104
ALA A 101
VAL A  98
 None
 1.50A 4ryaA-1uebA:
undetectable		 4ryaA-1uebA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ueb ELONGATION FACTOR P
(Thermus
thermophilus) 		4 / 7 GLY A 107
THR A 109
LEU A  85
MET A  83
 None
 0.86A 4zdzA-1uebA:
undetectable		 4zdzA-1uebA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1ueb ELONGATION FACTOR P
(Thermus
thermophilus) 		5 / 12 VAL A 132
GLU A 169
THR A 143
GLY A 138
LEU A 163
 None
 1.29A 5m50B-1uebA:
undetectable		 5m50B-1uebA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1ueb ELONGATION FACTOR P
(Thermus
thermophilus) 		5 / 12 VAL A 132
GLU A 169
THR A 143
GLY A 138
LEU A 163
 None
 1.26A 5m50E-1uebA:
undetectable		 5m50E-1uebA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 1ueb ELONGATION FACTOR P
(Thermus
thermophilus) 		5 / 12 ILE A 120
LEU A  70
PHE A  91
GLY A 117
ILE A  63
 None
 1.05A 6dwnC-1uebA:
undetectable		 6dwnC-1uebA:
20.11