SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ueq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 1ueq MEMBRANE ASSOCIATED
GUANYLATE KINASE
INVERTED-2 (MAGI-2)
(Homo
sapiens) 		5 / 11 GLY A  33
ALA A  57
ASP A  60
ILE A  72
THR A  65
 None
 1.03A 4l1aA-1ueqA:
undetectable		 4l1aA-1ueqA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ueq MEMBRANE ASSOCIATED
GUANYLATE KINASE
INVERTED-2 (MAGI-2)
(Homo
sapiens) 		4 / 6 PHE A  34
MET A  63
ILE A  36
VAL A  98
 None
 1.38A 4mk4B-1ueqA:
undetectable		 4mk4B-1ueqA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1ueq MEMBRANE ASSOCIATED
GUANYLATE KINASE
INVERTED-2 (MAGI-2)
(Homo
sapiens) 		4 / 7 ILE A  36
PHE A  34
VAL A  85
ILE A  72
 None
 0.73A 4zzbC-1ueqA:
undetectable
4zzbD-1ueqA:
undetectable		 4zzbC-1ueqA:
16.77
4zzbD-1ueqA:
16.77