SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uer'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 1uer SUPEROXIDE DISMUTASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 155
LEU A 153
VAL A 158
ASP A 157
GLY A 115
 None
None
None
FE  A 192 (-2.6A)
None
 1.14A 2f8lA-1uerA:
undetectable		 2f8lA-1uerA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1uer SUPEROXIDE DISMUTASE
(Porphyromonas
gingivalis) 		3 / 3 HIS A  74
ILE A   6
LEU A  53
 FE  A 192 (-3.3A)
None
None
 0.76A 2kceA-1uerA:
undetectable		 2kceA-1uerA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 1uer SUPEROXIDE DISMUTASE
(Porphyromonas
gingivalis) 		5 / 12 ASN A  75
ILE A  64
GLY A  63
ASN A 144
LEU A  53
 None
 1.16A 3eeyJ-1uerA:
undetectable		 3eeyJ-1uerA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1uer SUPEROXIDE DISMUTASE
(Porphyromonas
gingivalis) 		4 / 5 ILE A  43
GLY A  63
ILE A  56
LEU A  42
 None
 0.93A 5dzkd-1uerA:
undetectable
5dzkk-1uerA:
undetectable
5dzky-1uerA:
undetectable		 5dzkd-1uerA:
22.84
5dzkk-1uerA:
19.16
5dzky-1uerA:
1.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1uer SUPEROXIDE DISMUTASE
(Porphyromonas
gingivalis) 		5 / 7 GLY A  29
LEU A  32
ILE A   6
LEU A   8
ILE A 181
 None
 1.11A 5vkqA-1uerA:
undetectable
5vkqB-1uerA:
undetectable		 5vkqA-1uerA:
7.26
5vkqB-1uerA:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1uer SUPEROXIDE DISMUTASE
(Porphyromonas
gingivalis) 		5 / 8 GLY A  29
LEU A  32
ILE A   6
LEU A   8
ILE A 181
 None
 1.12A 5vkqB-1uerA:
undetectable
5vkqC-1uerA:
undetectable		 5vkqB-1uerA:
7.26
5vkqC-1uerA:
7.26