SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 12 PHE P 414
ILE P 100
PHE P  99
TYR P  80
PHE P  71
None
1.02A 1c9hA-1uf2P:
undetectable
1c9hA-1uf2P:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ILE A 541
ALA A 361
ILE A 654
LEU A1010
ARG A 523
None
1.25A 1dlsA-1uf2A:
undetectable
1dlsA-1uf2A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 ALA A 299
SER A 620
ARG A 741
LEU A 672
None
1.16A 1gahA-1uf2A:
undetectable
1gahA-1uf2A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 ASN A 737
ASP A 736
TRP A 735
TYR A 679
None
1.35A 1hpkA-1uf2A:
0.0
1hpkA-1uf2A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 GLU A 115
HIS A 110
ASP A 913
None
0.76A 1i9gA-1uf2A:
undetectable
1i9gA-1uf2A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 GLY A 372
GLN A 634
ALA A 402
SER A 370
None
1.01A 1p6kA-1uf2A:
undetectable
1p6kA-1uf2A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 TYR A 720
ASP A 668
ASN A 302
GLU A 723
None
0.88A 1rjdA-1uf2A:
undetectable
1rjdA-1uf2A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 TYR A 720
ASP A 668
ASN A 302
GLU A 723
None
0.87A 1rjdB-1uf2A:
undetectable
1rjdB-1uf2A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 TYR A 720
ASP A 668
ASN A 302
GLU A 723
None
0.86A 1rjdC-1uf2A:
undetectable
1rjdC-1uf2A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 LEU A 642
THR A 559
ILE A 562
SER A 589
PHE A 591
None
1.38A 1xomB-1uf2A:
undetectable
1xomB-1uf2A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 LEU A 642
THR A 559
ILE A 562
SER A 589
PHE A 591
None
1.40A 1xoqA-1uf2A:
undetectable
1xoqA-1uf2A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 LEU A 642
THR A 559
ILE A 562
SER A 589
PHE A 591
None
1.36A 1xoqB-1uf2A:
undetectable
1xoqB-1uf2A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 11 PHE P 414
ILE P 100
TYR P  80
LEU P  82
PHE P  71
None
1.23A 1yatA-1uf2P:
undetectable
1yatA-1uf2P:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 5 TYR P 360
PRO P 364
THR P 353
SER P 355
None
1.41A 1ymxA-1uf2P:
undetectable
1ymxA-1uf2P:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 5 LEU A 806
GLY A 954
ALA A 869
ILE A 867
None
0.78A 2aohB-1uf2A:
undetectable
2aohB-1uf2A:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 7 LEU P 273
GLY P 195
PRO P 212
VAL P 211
ILE P 278
None
1.42A 2aojB-1uf2P:
undetectable
2aojB-1uf2P:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 11 PHE P 414
ILE P 100
PHE P  99
TYR P  80
PHE P  71
None
1.07A 2dg4A-1uf2P:
undetectable
2dg4A-1uf2P:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 7 ARG P 189
GLU P 296
LYS P 129
PRO P 150
None
1.25A 2ejgA-1uf2P:
undetectable
2ejgA-1uf2P:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 GLN A 426
LEU A 419
ILE A 438
VAL A 437
ALA A 427
None
1.32A 2g72B-1uf2A:
undetectable
2g72B-1uf2A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 LEU A 463
ASN A 461
ARG A 431
None
0.79A 2qhfA-1uf2A:
undetectable
2qhfA-1uf2A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ILE A 601
ALA A 361
LEU A 356
GLN A 407
LEU A 403
None
1.09A 2rctA-1uf2A:
undetectable
2rctA-1uf2A:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 PHE A 778
VAL A 921
ALA A 813
ALA A 817
LEU A 907
None
1.31A 2x2nC-1uf2A:
0.3
2x2nC-1uf2A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 8 LEU A 462
ILE A 473
LEU A 469
THR A 428
None
0.69A 2xfhA-1uf2A:
undetectable
2xfhA-1uf2A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 LEU A 118
ILE A 706
LEU A 710
ILE A 754
VAL A 761
None
0.95A 2ygnA-1uf2A:
undetectable
2ygnA-1uf2A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 LEU A 518
ILE A 515
PRO A 367
VAL A 645
None
1.17A 2ygoA-1uf2A:
undetectable
2ygoA-1uf2A:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 MET A 317
ILE A 648
LEU A 315
ALA A 357
LEU A 641
None
1.18A 3a50A-1uf2A:
1.0
3a50A-1uf2A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 5 ASN A 500
ALA A 499
GLY A 498
TYR A 497
None
1.20A 3bcrA-1uf2A:
undetectable
3bcrA-1uf2A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ALA A 357
ILE A 605
ILE A 539
PRO A 538
ILE A 398
None
1.18A 3clbB-1uf2A:
undetectable
3clbB-1uf2A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ILE A 541
ALA A 361
ALA A 613
ILE A 654
LEU A1010
None
1.06A 3dauA-1uf2A:
undetectable
3dauA-1uf2A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 4 LEU A 345
MET A 317
ILE A 562
ASP A 593
None
1.35A 3hecA-1uf2A:
0.4
3hecA-1uf2A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 GLY A 277
GLY A 275
ASP A 204
ASP A 991
LEU A 279
None
0.90A 3ihtA-1uf2A:
undetectable
3ihtA-1uf2A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 8 ASP P 321
TYR P 307
VAL P 325
LEU P 132
None
0.75A 3jq7C-1uf2P:
undetectable
3jq7C-1uf2P:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 9 LEU P 273
VAL P 291
LEU P 282
PHE P 252
VAL P 254
None
1.27A 3jwqA-1uf2P:
undetectable
3jwqA-1uf2P:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 8 VAL A 141
LEU A  65
ILE A 985
VAL A 983
LEU A 229
None
1.25A 3kp6A-1uf2A:
0.7
3kp6B-1uf2A:
undetectable
3kp6A-1uf2A:
10.11
3kp6B-1uf2A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 8 LEU A 686
SER A 683
ILE A 693
PHE A 694
None
0.90A 3ln1A-1uf2A:
undetectable
3ln1A-1uf2A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 7 LEU A 686
SER A 683
ILE A 693
PHE A 694
None
0.90A 3ln1B-1uf2A:
0.0
3ln1B-1uf2A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 11 GLN A 395
PRO A 508
ASN A 412
ALA A 499
THR A 502
None
1.28A 3n23A-1uf2A:
undetectable
3n23A-1uf2A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 5 ASP A 946
GLU A 851
THR A 863
SER A  82
None
1.14A 3p2kC-1uf2A:
undetectable
3p2kC-1uf2A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 VAL A 248
ARG A 282
ILE A 201
VAL A 198
TYR A 217
None
1.47A 3p6gA-1uf2A:
undetectable
3p6gA-1uf2A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 7 ALA A 492
TYR A 497
ARG A 406
ALA A 405
None
1.12A 3twpB-1uf2A:
undetectable
3twpB-1uf2A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 8 ILE A 360
SER A 620
THR A 542
LEU A 510
None
0.84A 3ua5A-1uf2A:
0.0
3ua5A-1uf2A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ILE A 138
GLU A 212
TYR A 217
HIS A 218
VAL A 983
None
1.17A 4a97B-1uf2A:
0.9
4a97C-1uf2A:
1.0
4a97B-1uf2A:
15.35
4a97C-1uf2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 8 MET P  42
GLU P  14
GLU P  18
ARG P  22
None
1.14A 4bqfB-1uf2P:
undetectable
4bqfB-1uf2P:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 SER A 800
ILE A 847
ASN A 783
SER A 848
PHE A 862
None
1.30A 4c49A-1uf2A:
undetectable
4c49A-1uf2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 ARG A 192
HIS A 218
TYR A 143
None
0.97A 4fu8A-1uf2A:
undetectable
4fu8A-1uf2A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 ARG A 192
HIS A 218
TYR A 143
None
0.97A 4fu9A-1uf2A:
undetectable
4fu9A-1uf2A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 ILE A 796
TYR A 948
TYR A 889
PHE A 949
None
1.19A 4g10A-1uf2A:
undetectable
4g10A-1uf2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 ASP A 326
LEU A 345
VAL A 350
None
0.65A 4jecB-1uf2A:
undetectable
4jecB-1uf2A:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 ASP A 661
ASN A 612
SER A 305
None
0.58A 4obwA-1uf2A:
undetectable
4obwA-1uf2A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 PHE A 415
LEU A 455
TYR A 459
LEU A 462
ILE A 438
None
0.95A 4pd4C-1uf2A:
undetectable
4pd4C-1uf2A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 8 ILE P 400
LEU P 410
LEU P 352
ILE P  72
None
0.67A 4r38A-1uf2P:
undetectable
4r38A-1uf2P:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 8 ILE P 400
LEU P 410
LEU P 352
ILE P  72
None
0.70A 4r38D-1uf2P:
1.5
4r38D-1uf2P:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ASN A 412
GLY A 512
PHE A 477
ALA A 485
VAL A 456
None
1.35A 4ryaA-1uf2A:
undetectable
4ryaA-1uf2A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ASP A 410
LEU A 391
PHE A 359
LEU A 403
ILE A 411
None
0.97A 4x1fA-1uf2A:
undetectable
4x1fA-1uf2A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ASP A 410
LEU A 391
PHE A 359
LEU A 403
ILE A 411
None
1.01A 4x1gA-1uf2A:
undetectable
4x1gA-1uf2A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 5 GLY A 277
TYR A 243
GLU A 212
ASP A 991
None
1.33A 4xueA-1uf2A:
undetectable
4xueA-1uf2A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 8 PHE P  68
TRP P  86
TRP P   6
TYR P  80
None
1.39A 5amkA-1uf2P:
0.0
5amkA-1uf2P:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 12 PHE P 414
ILE P 100
TYR P  80
LEU P  82
PHE P  71
None
1.18A 5b8iC-1uf2P:
undetectable
5b8iC-1uf2P:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 GLU A 115
HIS A 110
ASP A 913
None
0.57A 5c0oG-1uf2A:
undetectable
5c0oG-1uf2A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 4 TYR A 889
ASN A 928
SER A  81
SER A  82
None
1.26A 5gsnC-1uf2A:
0.0
5gsnC-1uf2A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 12 PHE P 414
ILE P 100
PHE P  99
TYR P  80
PHE P  71
None
1.05A 5hkgA-1uf2P:
undetectable
5hkgA-1uf2P:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
5 / 11 PHE P 414
ILE P 100
TYR P  80
LEU P  82
PHE P  71
None
1.20A 5huaA-1uf2P:
undetectable
5huaA-1uf2P:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
3 / 3 ARG A 503
PRO A 514
ASN A 516
None
0.96A 5jwaA-1uf2A:
undetectable
5jwaH-1uf2A:
undetectable
5jwaA-1uf2A:
19.75
5jwaH-1uf2A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 5 ARG A 122
MET A 765
THR A 766
LEU A 768
None
1.33A 5x19J-1uf2A:
undetectable
5x19J-1uf2A:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 5 ARG A 122
MET A 765
THR A 766
LEU A 768
None
1.26A 5x1bJ-1uf2A:
undetectable
5x1bJ-1uf2A:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 11 ALA A  98
ASP A 879
VAL A 795
ILE A 925
ILE A 961
None
1.21A 5y80A-1uf2A:
0.0
5y80A-1uf2A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 ILE A 420
ASN A 413
TYR A 476
PHE A 382
LEU A 462
None
1.10A 6chgC-1uf2A:
undetectable
6chgC-1uf2A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 6 ARG A 536
ILE A 369
ASN A 368
ASP A 619
None
1.41A 6dhbA-1uf2A:
0.0
6dhbA-1uf2A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)
1uf2 OUTER CAPSID PROTEIN
P8

(Rice
dwarf
virus)
4 / 6 PHE P  71
ARG P  77
ILE P 104
ASP P  97
None
1.30A 6dhbA-1uf2P:
0.0
6dhbA-1uf2P:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
4 / 7 GLY A 388
ALA A 389
VAL A 645
LEU A 641
None
0.82A 6dwnB-1uf2A:
undetectable
6dwnB-1uf2A:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)
1uf2 CORE PROTEIN P3
(Rice
dwarf
virus)
5 / 12 LEU A 397
ILE A 398
ILE A 539
ILE A 601
ILE A 360
None
1.08A 6emuC-1uf2A:
undetectable
6emuC-1uf2A:
11.32