SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ugh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	1ugh	PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR) (Bacillus phage PBS2)	5 / 12	ILE I 41 THR I 59 VAL I 29 ILE I 33 PRO I 37	None	1.09A	3kpbA-1ughI: undetectable	3kpbA-1ughI: 24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_C_SAMC1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	1ugh	PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR) (Bacillus phage PBS2)	5 / 12	ILE I 41 THR I 59 VAL I 29 ILE I 33 PRO I 37	None	1.10A	3kpbC-1ughI: undetectable	3kpbC-1ughI: 24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPC_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	1ugh	PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR) (Bacillus phage PBS2)	5 / 11	ILE I 41 THR I 59 VAL I 29 ILE I 33 PRO I 37	None	1.22A	3kpcA-1ughI: undetectable	3kpcA-1ughI: 24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_B_SAMB1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	1ugh	PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR) (Bacillus phage PBS2)	5 / 12	ILE I 41 THR I 59 VAL I 29 ILE I 33 PRO I 37	None	1.19A	3kpdB-1ughI: undetectable	3kpdB-1ughI: 24.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KPB_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","1ugh","PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR)","Bacillus phage PBS2",5,"ILE I  41;THR I  59;VAL I  29;ILE I  33;PRO I  37","None","1.09A","3kpbA-1ughI:undetectable","3kpbA-1ughI:24.58"],["3KPB_C_SAMC1000_0","UNCHARACTERIZED PROTEIN MJ0100","1ugh","PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR)","Bacillus phage PBS2",5,"ILE I  41;THR I  59;VAL I  29;ILE I  33;PRO I  37","None","1.10A","3kpbC-1ughI:undetectable","3kpbC-1ughI:24.58"],["3KPC_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","1ugh","PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR)","Bacillus phage PBS2",5,"ILE I  41;THR I  59;VAL I  29;ILE I  33;PRO I  37","None","1.22A","3kpcA-1ughI:undetectable","3kpcA-1ughI:24.17"],["3KPD_B_SAMB1000_0","UNCHARACTERIZED PROTEIN MJ0100","1ugh","PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR)","Bacillus phage PBS2",5,"ILE I  41;THR I  59;VAL I  29;ILE I  33;PRO I  37","None","1.19A","3kpdB-1ughI:undetectable","3kpdB-1ughI:24.58"]]