SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ugk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 1ugk SYNAPTOTAGMIN IV
(Homo
sapiens) 		4 / 8 LEU A  15
LEU A  11
LEU A 126
ARG A 129
 None
 1.17A 2xn3A-1ugkA:
0.0
2xn3B-1ugkA:
0.0		 2xn3A-1ugkA:
17.48
2xn3B-1ugkA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1ugk SYNAPTOTAGMIN IV
(Homo
sapiens) 		6 / 12 LEU A 115
LEU A 120
ILE A 118
VAL A  26
LEU A  92
PHE A  13
 None
 1.38A 4y0sA-1ugkA:
undetectable		 4y0sA-1ugkA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 1ugk SYNAPTOTAGMIN IV
(Homo
sapiens) 		5 / 12 ILE A  96
PRO A  35
LEU A  34
SER A   5
GLY A 109
 None
 1.32A 5il1A-1ugkA:
undetectable		 5il1A-1ugkA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ugk SYNAPTOTAGMIN IV
(Homo
sapiens) 		3 / 3 THR A  68
THR A  62
LEU A  11
 None
 0.58A 5m66D-1ugkA:
undetectable		 5m66D-1ugkA:
12.86