SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ugo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.09A 1a52A-1ugoA:
undetectable		 1a52A-1ugoA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.11A 1a52B-1ugoA:
undetectable		 1a52B-1ugoA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 9 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.08A 1ereA-1ugoA:
undetectable		 1ereA-1ugoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 9 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.07A 1ereB-1ugoA:
undetectable		 1ereB-1ugoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 9 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.09A 1ereC-1ugoA:
undetectable		 1ereC-1ugoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 9 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.06A 1ereD-1ugoA:
undetectable		 1ereD-1ugoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 8 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.07A 1ereE-1ugoA:
undetectable		 1ereE-1ugoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 8 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.08A 1ereF-1ugoA:
undetectable		 1ereF-1ugoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.14A 1gwrA-1ugoA:
undetectable		 1gwrA-1ugoA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.12A 1pcgA-1ugoA:
undetectable		 1pcgA-1ugoA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.13A 1pcgB-1ugoA:
undetectable		 1pcgB-1ugoA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.20A 1qkuA-1ugoA:
undetectable		 1qkuA-1ugoA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.20A 1qkuB-1ugoA:
undetectable		 1qkuB-1ugoA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.21A 1qkuC-1ugoA:
undetectable		 1qkuC-1ugoA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 12 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.10A 2yjaB-1ugoA:
undetectable		 2yjaB-1ugoA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 12 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.13A 3erdA-1ugoA:
undetectable		 3erdA-1ugoA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 12 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.08A 3hm1A-1ugoA:
undetectable		 3hm1A-1ugoA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 12 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.12A 3olsA-1ugoA:
undetectable		 3olsA-1ugoA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 12 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.10A 3olsB-1ugoA:
undetectable		 3olsB-1ugoA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 11 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.09A 3uudA-1ugoA:
undetectable		 3uudA-1ugoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.09A 3uudB-1ugoA:
undetectable		 3uudB-1ugoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 12 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.07A 4pxmA-1ugoA:
undetectable		 4pxmA-1ugoA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 11 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.07A 5dxbB-1ugoA:
undetectable		 5dxbB-1ugoA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.08A 5dxeB-1ugoA:
undetectable		 5dxeB-1ugoA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 11 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.10A 5dxgB-1ugoA:
undetectable		 5dxgB-1ugoA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.08A 5hyrA-1ugoA:
undetectable		 5hyrA-1ugoA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 11 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.11A 5hyrB-1ugoA:
undetectable		 5hyrB-1ugoA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 9 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.06A 5wgdA-1ugoA:
undetectable		 5wgdA-1ugoA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1ugo BCL2-ASSOCIATED
ATHANOGENE 5
(Mus
musculus) 		5 / 10 ALA A  79
GLU A  83
LEU A  57
LEU A  53
LEU A  20
 None
 1.05A 5wgqB-1ugoA:
undetectable		 5wgqB-1ugoA:
22.73